Senior cardiac Work, Jobs in Eng (with Salaries)

Senior scientist
Cora Biosciences —London
- Full-time
- Doctoral degree
- Data analysis skills
- Laboratory experience
Quick apply
Senior Fellow in Paediatric Intensive Care
University Hospital Southampton NHS Foundation Trust —Southampton
- £65,048 - £73,992 a year
- Weekend availability
- No experience needed
- English
- ICU experience
- Annual leave
- Employee discount
11d
Senior Research Fellow in Cardiac Electrophysiology Modelling (Fixed-term)
University of Nottingham —Nottingham
- £46,049 - £48,822 a year
- Full-time
- Doctoral degree
- Organisational skills
- Communication skills
- Flexible schedule
Senior Chief Cardiac Physiologist
The Princess Alexandra Hospital NHS Trust —Harlow
- £49,387 - £56,515 a year
10d
Senior Clinical Fellow
Northampton General Hospital NHS Trust —Northampton
- £67,325 a year
- Weekend availability
- ICU experience
7d
Senior Cardiac Physiologist – Non Invasive
HCA Healthcare UK —London
- Full-time
- Employee discount
- Flexible schedule
4d
Sessional Lecturer
Hammersmith & Fulham Council —Hammersmith
- £29.64 - £36.03 an hour
- Weekend availability
- Spanish
- Management
- Psychology
Senior Radiographer – Cardiac MRI
Circle Health Group —Cheadle
- Full-time
- Hospital
- Customer service
- IT
- Employee discount
- Life insurance
5d
Cardiac Physiologist
Chelsea and Westminster Hospital NHS Foundation Trust —London
- £38,488 - £46,852 a year
- Weekend availability
10d
Senior Cardiac Physiologist
Hampshire Hospitals NHS Foundation Trust —Basingstoke
- £38,682 - £46,580 a year
- Full-time
3d
Senior Cardiac Cath Lab Radiographer
Bupa —London
- Weekend availability
- Hospital
- Laboratory experience
- Bachelor's degree
- Employee discount
- Gym membership
Quick apply
Chief Cardiac Physiologist
The Princess Alexandra Hospital NHS Trust —Harlow
- £39,959 - £48,117 a year
4d
Healthcare Project Manager
HCA Healthcare UK —Manchester
- From £6,500 a month
- Full-time
- Hospital
- Organisational skills
- In-person
- Health & wellbeing programme
- Relocation assistance
Quick apply
6d
Cardiac Surgery Chief Perfusionist
Nottingham University Hospitals NHS Trust —Nottingham
- £79,504 - £91,609 a year
- Full-time
- University
- Leadership
4d
Senior Theatre Practitioner Scrub - Cardiac Thoracic
Bupa —London
- £46,195 - £54,700 a year
- Weekend availability
- Gym membership
- Life insurance
Quick apply
10d
Trial Vendor Senior Manager - Global Clinical Operations
Novartis —London
- £49,140 - £91,260 a year
- Full-time
- Hybrid work
- Bachelor's degree
- Communication skills
Senior Cardiac Physiologist
University Hospitals Sussex NHS Foundation Trust —Chichester
- £39,959 - £48,117 a year
- Full-time
17h
Resident ICU Fellow - FTC
The London Clinic —London
- Full-time
- ICU experience
- Organisational skills
- Communication skills
- Employee discount
Specialist Senior Echo Physiologist - Bank Shifts
Bupa —London
- Part-time
- Master's degree
- Bachelor's degree
- Annual leave
- Gym membership
Quick apply
Senior Rota Co-ordinator
Leeds Teaching Hospitals NHS Trust —Leeds
- £32,073 - £39,043 a year
- Full-time
- Hospital
- Teaching
- Annual leave
3d

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Senior scientist

Cora Biosciences
London

Quick apply

Job details

Full-time

Qualifications

Biology
Clinical research
Doctoral degree
Scientific research
Data analysis skills
Laboratory experience
Bachelor's degree
Biochemistry
Communication skills

Full job description

About Cora Biosciences

We are a newly launched, venture-backed biotech spinout from a leading academic institution, dedicated to transforming the treatment of serious diseases using next-generation antisense oligonucleotide (ASO) therapeutics. With a strong scientific foundation and a leadership team of experienced drug developers, we are building a pipeline of RNA-targeted therapies that address high unmet medical need.

We are seeking a Senior Scientist – Discovery Biology to join our founding research team in London. This is a unique opportunity to help shape the scientific direction of an early-stage company while making meaningful contributions to the development of novel ASO therapeutics.

Role Overview

We are seeking a highly motivated and skilled Senior Scientist to join our team. The successful candidate will lead the biological evaluation of antisense oligonucleotides from early discovery through lead identification for cardiac therapeutic applications. This is role is responsible for developing and executing ASO screening cascades, building disease-relevant in vitro and in vivo models, and driving the biological characterization of candidate molecules.

You will work cross-functionally with chemistry, bioinformatics, and translational teams to advance our early pipeline, helping to define the next generation of RNA-targeted therapies.

Key Responsibilities

Design, develop, and implement high-throughput in vitro screening assays for ASO activity, selectivity, uptake, and toxicity.
Build and validate disease-relevant cellular and molecular models (e.g., primary cells, iPSC-derived models, organoids, etc.) for ASO screening and mechanistic studies.
Lead the biological evaluation of ASO candidates to support lead optimization and candidate selection.
Design and execute in vivo pharmacology studies to assess ASO distribution, target engagement, efficacy, and safety.
Collaborate with medicinal chemists and bioinformaticians to support target validation, RNA expression analysis, and biomarker identification.
Interpret complex biological datasets and communicate findings clearly to internal stakeholders and external collaborators.
Organise, analyse and interpret internal research data to identify key insights that will inform future research activities and business strategy and clearly communicating these to relevant internal stakeholders.
Mentor junior scientists and contribute to building a high-performing research team and culture.
Maintaining high standards of accuracy, confidentiality, and security when handling sensitive data related to proprietary research findings.

Required Qualifications

PhD in Molecular Biology, Cell Biology, Pharmacology, or a related field, with 4+ years of relevant postdoctoral or industry experience.
Proven expertise in nucleic acid therapeutics, especially ASOs.
Strong track record in molecular and cellular biology assay development, including vector design, psiCHECK, QuantiGene assays, qPCR, RT-PCR, ddPCR, Western blotting, ELISA, immunocytochemistry, microscopy, splint ligation, hELISA, RNAscope and transcriptome analysis.
Hands-on experience with cell-based disease models, especially in cardiac diseases.
Experience in developing transgenic mouse models.
Experience designing and executing in vivo studies in rodents for ASO or RNA therapeutic evaluation.
Familiarity with ASO delivery, uptake, and metabolism in various tissues.
Excellent experimental design, data analysis, and problem-solving skills.
Strong written and verbal communication skills; ability to clearly present scientific data and strategies.
Ability to work in a fast-paced, collaborative startup environment.

Preferred Qualifications

Experience in early-stage drug discovery or biotech startups.
Knowledge of RNA biology, splicing regulation, or RNA-protein interactions.
Experience with high-content imaging, single-cell RNAseq, or transcriptomics.

Why Join Us

Competitive salary and benefits package.
Opportunity to be part of an early-stage team shaping the future of a high-impact biotech startup.
Work at the intersection of cutting-edge science and unmet clinical need.
Thrive in a fast-paced, collaborative, and supportive startup environment.
Modern lab and office space in the heart of London's biotech ecosystem.

How to Apply

Please submit your CV and a brief cover letter outlining your interest and relevant experience to: [email protected] Applications will be reviewed on a rolling basis with the aim to fill the position promptly. Therefore, we encourage qualified individuals to submit their applications without delay.

Job Type: Full-time

Work Location: In person

Quick apply

Refine Your Search

senior cardiac jobs in eng

Senior scientist

Senior Fellow in Paediatric Intensive Care

Senior Research Fellow in Cardiac Electrophysiology Modelling (Fixed-term)

Senior Chief Cardiac Physiologist

Senior Clinical Fellow

Senior Cardiac Physiologist – Non Invasive

Sessional Lecturer

Senior Radiographer – Cardiac MRI

Cardiac Physiologist

Senior Cardiac Physiologist

Senior Cardiac Cath Lab Radiographer

Chief Cardiac Physiologist

Healthcare Project Manager

Cardiac Surgery Chief Perfusionist

Senior Theatre Practitioner Scrub - Cardiac Thoracic

Trial Vendor Senior Manager - Global Clinical Operations

Senior Cardiac Physiologist

Resident ICU Fellow - FTC

Specialist Senior Echo Physiologist - Bank Shifts

Senior Rota Co-ordinator

I want to receive the latest job alerts for senior cardiac in eng

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