Scientist i, r&d ast discs Work, Jobs in Tilehurst, Brk (with Salaries)

Scientist - Cell Biology
T-Cypher Bio —Abingdon
- Full-time
- Doctoral degree
- Laboratory experience
- Master's degree
Quick apply
7d
Scientific Technician / Research Associate
Wild Bioscience —Milton
- Full-time
- Data analysis skills
- Laboratory experience
- Master's degree
Quick apply
11d
Applied Biodiversity Scientist
Centre for Ecology & Hydrology —Wallingford
- £40,574 - £43,056 a year
- Full-time
- Hybrid work
- Doctoral degree
- Communication skills
- Annual leave
- Employee assistance programme
Junior/Associate Scientist
MoA Technology —Oxford
- Full-time
- Microsoft Powerpoint
- Microsoft Word
- Microsoft Outlook
- Annual leave
- Employee assistance programme
5d
Research Assistant in Urinary Tract Infection Biology
University of Oxford —Oxford
- £35,681 - £40,514 a year
- Master's degree
- University
- Bachelor's degree
- Annual leave
7d
Scientist - Molecular Validation, Fixed term contract 12 months
Enara Bio —Oxford
- Doctoral degree
- Data analysis skills
- Laboratory experience
Quick apply
11d
Postdoctoral Research Scientist – Chemical Synthesis for Advanced Therapeutics
University of Oxford —Oxford
- £39,424 - £47,779 a year
- Full-time
- Doctoral degree
- Organisational skills
- Annual leave
- Employee assistance programme
14d
Senior Scientist, Analytical Development
Replimune —Abingdon
- Full-time
- Doctoral degree
- Computer literacy
- Master's degree
Quick apply
7d
Scientist, Clinical Biomarker Laboratory, Immuno-Assays - Cell Based
Moderna, Inc. —Oxford
- Weekend availability
- Microsoft Powerpoint
- Doctoral degree
- Data analysis skills
- Annual leave
Research Associate in Secondary I...
The Rosalind Franklin Institute —Harwell
- £38,500 - £39,500 a year
- Full-time
- Doctoral degree
- Leadership
- Free parking
- Annual leave
Quality Control Chemist
Biosynth Carbosynth —Newbury
- £28,000 - £29,000 a year
- Full-time
- Computer literacy
- Laboratory experience
- Bachelor's degree
- Free parking
- Sick pay
Quick apply
3d
Associate Scientist, Analytical
MedPharm —Guildford
- Full-time
- Computer literacy
- Laboratory experience
- Microsoft Office
Quick apply
12d
Research Assistant in neuron-astrocyte communication in neurodegeneration
University of Oxford —Oxford
- £35,681 - £39,424 a year
- Full-time
- Master's degree
- Administrative experience
- Bachelor's degree
6d
QC Scientist
Lonza —Slough
- Full-time
- Laboratory experience
- Analysis skills
- Continuous improvement
19h
Senior Scientist I, High Throughput Assays
Immunocore —Abingdon
- Doctoral degree
- Master's degree
- Bachelor's degree
11d
Research Biologist
Syngenta Crop Protection —Bracknell
- Full-time
- Microsoft Office
- Bachelor's degree
- Organisational skills
- Life insurance
Quick apply
4h
Graduate Acoustic Stealth Scientist
QinetiQ —Farnborough
- £40,050 - £44,500 a year
- Full-time
- Analysis skills
- Communication skills
- Time management
- Employee discount
Research Assistant
University of Oxford —Oxford
- £35,681 - £46,476 a year
- Full-time
- Data analysis skills
- Laboratory experience
- Travel
6d
Senior Research Scientist I - Infectious Diseases
Immunocore —Oxford
- Full-time
- Doctoral degree
- Master's degree
- Presentation skills
Senior Research Scientist
Milvus Advanced —Oxford
- £40,000 - £50,000 a year
- Full-time
- Doctoral degree
- In-person
- Communication skills
- Free parking
- Relocation assistance
Quick apply
5d

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Scientist - Cell Biology

T-Cypher Bio
Abingdon

Quick apply

Job details

Full-time
7 days ago

Qualifications

Biology
Doctoral degree
Laboratory experience
Master's degree
Presentation skills
Organisational skills
Communication skills

Full job description

T-Cypher Bio is an early-stage, innovative biotechnology company aiming to unlock an expansive target space to build a pipeline of novel, T-cell receptor (TCR)-based therapeutics. We are seeking a highly motivated and detail-oriented Scientist to join our Translational Cell Biology team. The successful candidate will contribute to the discovery and development of novel cancer therapeutics by executing in vitro and ex vivo experiments to understand tumor biology, mechanism of action, and therapeutic response.

What you will do

The primary focus of this role will be to execute experiments establishing and characterizing primary tumor cultures and normal cells from clinical patient samples. The ideal candidate should have hands on experience culturing mammalian cells under sterile conditions and have a keen interest in cancer biology.

Key Responsibilities

Perform enzymatic and mechanical dissociation of solid tumor tissues (e.g., PDX, primary patient biopsies) into single-cell suspensions using established protocols.
Optimize dissociation protocols for different tumour types to preserve cell viability, heterogeneity, and functional characteristics.
Isolate specific cell populations (e.g., cancer cells, immune cells, stromal components) as needed using techniques such as magnetic bead sorting or flow cytometry.
Isolate and cryopreserve PBMCs from patient and healthy donor blood samples.
Establish and maintain cultures of primary tumor and normal cells.
Maintain and expand cultures of single cell clones that have been established from modified cancer cell lines.
Monitor cell health, morphology, and growth dynamics; passage and cryopreserve cell stocks.
Extraction of RNA and DNA from cell lines or patient samples for analysis
Customize media formulations and supplements to support long-term viability and functional integrity of tumour cultures.
Prioritisation of personal workloads and coordination of scientific work streams and processes.
Analyse and record experimental results and communicate findings to the team and to management.
Maintain and implement good laboratory practices, including accurate laboratory notebook systems, instrument and reagent maintenance, and personnel safety precautions.

To be successful you will need

Master’s degree with relevant experience or PhD in Cell Biology, Molecular Biology, Cancer Biology, or a related life science field
1+ year of laboratory experience in a cancer biology or tissue culture setting, ideally in industry or translational research
Proficiency in cell-based assays and molecular biology techniques
Experience with dissociation of tissue samples into single-cell suspensions would be advantageous
Strong attention to detail and ability to troubleshoot and optimize protocols
Excellent teamwork, organizational, and communication skills
Analysing and presenting results in a concise and accurate manner to the wider team

Ability to adapt to multiple roles in a matrixed, fast-paced and evolving company
Enjoy working towards challenging goals in a fast-moving environment
Ability to follow and write protocols and SOPs
Knowledge of health and safety regulations in a laboratory environment

What we offer

Competitive salary and benefits commensurate with qualifications and experience.

Modern, well-equipped office and laboratory facilities on Abingdon Science Park.

Training and development opportunities in-line with the company’s goals and growth plans.

An exciting opportunity to help establish an early-stage biotech with ambitions to impact patients’ lives.

How to apply

Applications will be evaluated in the order that they are received, you are encouraged to apply as soon as possible.

Applications will close once the position is filled.

Quick apply

Refine Your Search

scientist i, r&d ast discs jobs in tilehurst, brk

Scientist - Cell Biology

Scientific Technician / Research Associate

Applied Biodiversity Scientist

Junior/Associate Scientist

Research Assistant in Urinary Tract Infection Biology

Scientist - Molecular Validation, Fixed term contract 12 months

Postdoctoral Research Scientist – Chemical Synthesis for Advanced Therapeutics

Senior Scientist, Analytical Development

Scientist, Clinical Biomarker Laboratory, Immuno-Assays - Cell Based

Research Associate in Secondary I...

Quality Control Chemist

Associate Scientist, Analytical

Research Assistant in neuron-astrocyte communication in neurodegeneration

QC Scientist

Senior Scientist I, High Throughput Assays

Research Biologist

Graduate Acoustic Stealth Scientist

Research Assistant

Senior Research Scientist I - Infectious Diseases

Senior Research Scientist

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