For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.
At Charles River, we take a passionate approach to improving human and animal health. Our motivating force is the knowledge that our high quality of work provides people with the potential to live healthier and better lives. Scientific excellence and outstanding customer service are the hallmarks of Charles River.
The ADME department provides support to the pharmaceutical, veterinary pharmaceutical and chemical/agrochemical industries by evaluating the metabolism and disposition of new chemical and biological entities in vivo in a variety of test species.
We are looking to recruit a Senior Scientific Associate to join the ADME team. As a Senior Scientific Associate in this team, your primary role will be to work within the animal health sector designing and managing studies to determine the ADME properties of new potential medicines in livestock species. Working in close contact with our clients, the departmental management team and the internal Charles River services you will be expected to contribute in the development of suitable study protocols to support the smooth and swift progression of drug candidates through preclinical evaluation and beyond.
You will be expected to have direct hands-on experience of conducting metabolism related studies, ideally involving the use of radio labelled entities, within academia or preferably in either the animal health or in contract research industry.
You may be required to coordinate and supervise the work of other staff within the department. You will also contribute to the ongoing business plan for the department, developing and marketing new services and be actively involved in staff training and assessment.
Applicants will be expected to be educated to at least degree level in biology or a life science subject.
Salary for this position is £35,264.70 per annum.
Performs technical laboratory activities in support of client studies or procedures. Performs analysis of data for quality and completeness and determines if results are as expected. Records data in compliance with company and regulatory policies and standards to meet quality and accuracy requirements. Executes scientific testing strategies and studies. May participate in development as part of team. May lead assay research, assay validation or study conduct, or is involved in preparation of material (e.g. protein, nucleic acid, cells, etc.). Reviews and interprets study data, communicates results to clients and writes final reports. Ensures compliance with protocols and all applicable SOPs. Troubleshoots and resolves assay or technical issues in the laboratory when scientific expertise is needed. Contributes to specific dataset interpretation, or when appropriate answering questions from regulatory authorities. For singular focus of Chemistry or Biology disciplines, refer to specified role on job architecture.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to fostering a sense of belonging and work daily in this direction.
