Senior scientist Work, Jobs in Chesham, Bkm (with Salaries)

Senior scientist
Cora Biosciences —London
- Full-time
- Doctoral degree
- Data analysis skills
- Laboratory experience
Quick apply
Senior Scientist
Lonza —Slough
- Full-time
- Engineering
- Data analysis skills
- Laboratory experience
Junior Product Development Scientist
pladis —High Wycombe
- Full-time
- Employee assistance programme
- Employee discount
Senior Safety Scientist / Associate Director / Director
Roche —Welwyn
- Doctoral degree
- Master's degree
- Presentation skills
Head of Virology (ID4520)
Animal and Plant Health Agency —New Haw
- £73,165 - £81,535 a year
- Overtime
- Doctoral degree
- Presentation skills
- Leadership
- Annual leave
- Employee discount
2d
Senior Scientist - R&D (G08)
Lonza —Slough
- Full-time
- Engineering
- Data analysis skills
- Laboratory experience
Senior Scientist (InSPIREmed) - £46,160-£51,666 p.a. + benefits
Medicines and Healthcare Products Regulatory Agency —South Mimms
- £46,160 - £51,666 a year
- Full-time
- Presentation skills
- Travel
- Annual leave
- Sick pay
3d
Senior Water Scientist and Hydrologist
AECOM —St Albans
- Full-time
- Hybrid work
Senior Scientist
SAVA —London
- Laboratory experience
- Bachelor's degree
Quick apply
Consultant Virologist
Ashford and St. Peter's Hospitals NHS Foundation Trust —Chertsey
- £105,504 - £139,882 a year
- Full-time
- Hospital
- Annual leave
- Employee discount
Senior Metabolomics Bioinformatician
Syngenta Crop Protection —Bracknell
- Full-time
- Doctoral degree
- Data analysis skills
- Machine learning
- Life insurance
Quick apply
Senior Director, Translational Genetics
GlaxoSmithKline —Stevenage
- £207,075 - £345,125 a year
- Full-time
- Management
- Doctoral degree
- Machine learning
- Annual leave
8d
Senior Scientist, Macrophage-stromal biology
Engitix —London
- Doctoral degree
- Master's degree
- IT
Quick apply
Senior Statistician
UK Health Security Agency —Colindale
- £60,494 - £70,566 a year
- Part-time
- Hybrid work
- Doctoral degree
- Data analysis skills
- Laboratory experience
13d
Director, Preclinical External Innovation
LifeArc —London
- Full-time
- Doctoral degree
- Leadership
- Communication skills
- Annual leave
Higher/Senior Scientist in Quantum Computing and Machine Learning
NPL —Teddington
- Doctoral degree
- Machine learning
- Leadership
Senior Technical Expert Toxicology
Syngenta Crop Protection —Bracknell
- Full-time
- Hybrid work
- Doctoral degree
- Master's degree
- Bachelor's degree
- Life insurance
Quick apply
Water Scientist – Nature Based Solution
Zora Ecosystems —London
- Doctoral degree
- Data analysis skills
- AWS
Quick apply
Machine Learning Scientist - Quantum Chemistry
Roche —Welwyn
- Hybrid work
- Doctoral degree
- Machine learning
- Travel
Senior Hydrogeologist
AECOM —St Albans
- Full-time
- Hybrid work
- Master's degree
- Bachelor's degree

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Senior scientist

Cora Biosciences
London

Quick apply

Job details

Full-time

Qualifications

Biology
Clinical research
Doctoral degree
Scientific research
Data analysis skills
Laboratory experience
Bachelor's degree
Biochemistry
Communication skills

Full job description

About Cora Biosciences

We are a newly launched, venture-backed biotech spinout from a leading academic institution, dedicated to transforming the treatment of serious diseases using next-generation antisense oligonucleotide (ASO) therapeutics. With a strong scientific foundation and a leadership team of experienced drug developers, we are building a pipeline of RNA-targeted therapies that address high unmet medical need.

We are seeking a Senior Scientist – Discovery Biology to join our founding research team in London. This is a unique opportunity to help shape the scientific direction of an early-stage company while making meaningful contributions to the development of novel ASO therapeutics.

Role Overview

We are seeking a highly motivated and skilled Senior Scientist to join our team. The successful candidate will lead the biological evaluation of antisense oligonucleotides from early discovery through lead identification for cardiac therapeutic applications. This is role is responsible for developing and executing ASO screening cascades, building disease-relevant in vitro and in vivo models, and driving the biological characterization of candidate molecules.

You will work cross-functionally with chemistry, bioinformatics, and translational teams to advance our early pipeline, helping to define the next generation of RNA-targeted therapies.

Key Responsibilities

Design, develop, and implement high-throughput in vitro screening assays for ASO activity, selectivity, uptake, and toxicity.
Build and validate disease-relevant cellular and molecular models (e.g., primary cells, iPSC-derived models, organoids, etc.) for ASO screening and mechanistic studies.
Lead the biological evaluation of ASO candidates to support lead optimization and candidate selection.
Design and execute in vivo pharmacology studies to assess ASO distribution, target engagement, efficacy, and safety.
Collaborate with medicinal chemists and bioinformaticians to support target validation, RNA expression analysis, and biomarker identification.
Interpret complex biological datasets and communicate findings clearly to internal stakeholders and external collaborators.
Organise, analyse and interpret internal research data to identify key insights that will inform future research activities and business strategy and clearly communicating these to relevant internal stakeholders.
Mentor junior scientists and contribute to building a high-performing research team and culture.
Maintaining high standards of accuracy, confidentiality, and security when handling sensitive data related to proprietary research findings.

Required Qualifications

PhD in Molecular Biology, Cell Biology, Pharmacology, or a related field, with 4+ years of relevant postdoctoral or industry experience.
Proven expertise in nucleic acid therapeutics, especially ASOs.
Strong track record in molecular and cellular biology assay development, including vector design, psiCHECK, QuantiGene assays, qPCR, RT-PCR, ddPCR, Western blotting, ELISA, immunocytochemistry, microscopy, splint ligation, hELISA, RNAscope and transcriptome analysis.
Hands-on experience with cell-based disease models, especially in cardiac diseases.
Experience in developing transgenic mouse models.
Experience designing and executing in vivo studies in rodents for ASO or RNA therapeutic evaluation.
Familiarity with ASO delivery, uptake, and metabolism in various tissues.
Excellent experimental design, data analysis, and problem-solving skills.
Strong written and verbal communication skills; ability to clearly present scientific data and strategies.
Ability to work in a fast-paced, collaborative startup environment.

Preferred Qualifications

Experience in early-stage drug discovery or biotech startups.
Knowledge of RNA biology, splicing regulation, or RNA-protein interactions.
Experience with high-content imaging, single-cell RNAseq, or transcriptomics.

Why Join Us

Competitive salary and benefits package.
Opportunity to be part of an early-stage team shaping the future of a high-impact biotech startup.
Work at the intersection of cutting-edge science and unmet clinical need.
Thrive in a fast-paced, collaborative, and supportive startup environment.
Modern lab and office space in the heart of London's biotech ecosystem.

How to Apply

Please submit your CV and a brief cover letter outlining your interest and relevant experience to: [email protected] Applications will be reviewed on a rolling basis with the aim to fill the position promptly. Therefore, we encourage qualified individuals to submit their applications without delay.

Job Type: Full-time

Work Location: In person

Quick apply

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senior scientist jobs in chesham, bkm

Senior scientist

Senior Scientist

Junior Product Development Scientist

Senior Safety Scientist / Associate Director / Director

Head of Virology (ID4520)

Senior Scientist - R&D (G08)

Senior Scientist (InSPIREmed) - £46,160-£51,666 p.a. + benefits

Senior Water Scientist and Hydrologist

Senior Scientist

Consultant Virologist

Senior Metabolomics Bioinformatician

Senior Director, Translational Genetics

Senior Scientist, Macrophage-stromal biology

Senior Statistician

Director, Preclinical External Innovation

Higher/Senior Scientist in Quantum Computing and Machine Learning

Senior Technical Expert Toxicology

Water Scientist – Nature Based Solution

Machine Learning Scientist - Quantum Chemistry

Senior Hydrogeologist

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