Clinical research scientist Work, Jobs in Oxford, Eng (with Salaries)

Scientist - Cell Biology
T-Cypher Bio —Abingdon
- Full-time
- Doctoral degree
- Laboratory experience
- Master's degree
Quick apply
6d
Research Assistant - Centralised National Virtual Clinic
University of Oxford —Oxford
- £35,681 - £41,636 a year
- Remote
- Psychology
- Organisational skills
- Annual leave
12d
Clinical Research Fellow
University of Oxford —Oxford
- £38,831 - £73,992 a year
- Full-time
- IT
13d
Senior Research Scientist I - Infectious Diseases
Immunocore —Oxford
- Full-time
- Doctoral degree
- Master's degree
- Presentation skills
Principal Research Associate, Clinical Biomarker Laboratory, Flow Cytometry
Moderna, Inc. —Oxford
- Weekend availability
- Microsoft Powerpoint
- Microsoft Word
- Microsoft Excel
- Annual leave
Clinical Biospecimen Scientist - Single Sponsor Dedicated
IQVIA —Reading
- Full-time
- Remote
- Bachelor's degree
- Work from home
Research Scientist – Autoimmune Research
Immunocore —Oxford
- Doctoral degree
- AI
- Communication skills
Senior Research Associate, Bioanalytical & Molecular Assays
Moderna, Inc. —Oxford
- Full-time
- Data analysis skills
- Bachelor's degree
- Annual leave
Principal Scientist, Bioanalytical & Molecular Assays
Moderna, Inc. —Oxford
- Full-time
- Doctoral degree
- Master's degree
- Annual leave
Specialist Biomedical Scientist (x2)
Deciphex —Oxford
- 8 hour shift
- Laboratory experience
- Mentoring
- Annual leave
Quick apply
Research Assistant in neuron-astrocyte communication in neurodegeneration
University of Oxford —Oxford
- £35,681 - £39,424 a year
- Full-time
- Master's degree
- Administrative experience
- Bachelor's degree
6d
Research Technician in Clinical Islet Isolation and Transplantation (Maternity Cover)
University of Oxford —Oxford
- £28,437 - £32,108 a year
- Full-time
- Laboratory experience
- Communication skills
6d
Senior Scientist, Analytical Development
Replimune —Abingdon
- Full-time
- Doctoral degree
- Computer literacy
- Master's degree
Quick apply
6d
Laboratory Operations Assistant
Revvity —Abingdon
- Part-time
- Microsoft Powerpoint
- Microsoft Excel
- Laboratory experience
Scientist
Genomics —Oxford
- Full-time
- Hybrid work
- Machine learning
- Python
- Annual leave
Postdoctoral Researcher in Big Data for Cardiovascular Population Health
University of Oxford —Oxford
- £39,424 a year
- Full-time
- Doctoral degree
- Machine learning
- SharePoint
- Annual leave
- Employee discount
3d
Senior Bioinformatician in Single-cell and Spatial Multiomics
University of Oxford —Oxford
- £49,119 - £55,031 a year
- Full-time
- Doctoral degree
- Data analysis skills
- Machine learning
- Annual leave
Principal Scientist
LGC Group —Kidlington
- Full-time
- Microsoft Powerpoint
- Microsoft Word
- Doctoral degree
Quick apply
7d
Senior Biomedical Scientist
Deciphex —Oxford
- 8 hour shift
- Data analysis skills
- Laboratory experience
- English
- Flexible schedule
Quick apply
Scientist II
OGT —Oxford
- Doctoral degree
- Bachelor's degree
- IT
- Employee discount
Quick apply

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Scientist - Cell Biology

T-Cypher Bio
Abingdon

Quick apply

Job details

Full-time
6 days ago

Qualifications

Biology
Doctoral degree
Laboratory experience
Master's degree
Presentation skills
Organisational skills
Communication skills

Full job description

T-Cypher Bio is an early-stage, innovative biotechnology company aiming to unlock an expansive target space to build a pipeline of novel, T-cell receptor (TCR)-based therapeutics. We are seeking a highly motivated and detail-oriented Scientist to join our Translational Cell Biology team. The successful candidate will contribute to the discovery and development of novel cancer therapeutics by executing in vitro and ex vivo experiments to understand tumor biology, mechanism of action, and therapeutic response.

What you will do

The primary focus of this role will be to execute experiments establishing and characterizing primary tumor cultures and normal cells from clinical patient samples. The ideal candidate should have hands on experience culturing mammalian cells under sterile conditions and have a keen interest in cancer biology.

Key Responsibilities

Perform enzymatic and mechanical dissociation of solid tumor tissues (e.g., PDX, primary patient biopsies) into single-cell suspensions using established protocols.
Optimize dissociation protocols for different tumour types to preserve cell viability, heterogeneity, and functional characteristics.
Isolate specific cell populations (e.g., cancer cells, immune cells, stromal components) as needed using techniques such as magnetic bead sorting or flow cytometry.
Isolate and cryopreserve PBMCs from patient and healthy donor blood samples.
Establish and maintain cultures of primary tumor and normal cells.
Maintain and expand cultures of single cell clones that have been established from modified cancer cell lines.
Monitor cell health, morphology, and growth dynamics; passage and cryopreserve cell stocks.
Extraction of RNA and DNA from cell lines or patient samples for analysis
Customize media formulations and supplements to support long-term viability and functional integrity of tumour cultures.
Prioritisation of personal workloads and coordination of scientific work streams and processes.
Analyse and record experimental results and communicate findings to the team and to management.
Maintain and implement good laboratory practices, including accurate laboratory notebook systems, instrument and reagent maintenance, and personnel safety precautions.

To be successful you will need

Master’s degree with relevant experience or PhD in Cell Biology, Molecular Biology, Cancer Biology, or a related life science field
1+ year of laboratory experience in a cancer biology or tissue culture setting, ideally in industry or translational research
Proficiency in cell-based assays and molecular biology techniques
Experience with dissociation of tissue samples into single-cell suspensions would be advantageous
Strong attention to detail and ability to troubleshoot and optimize protocols
Excellent teamwork, organizational, and communication skills
Analysing and presenting results in a concise and accurate manner to the wider team

Ability to adapt to multiple roles in a matrixed, fast-paced and evolving company
Enjoy working towards challenging goals in a fast-moving environment
Ability to follow and write protocols and SOPs
Knowledge of health and safety regulations in a laboratory environment

What we offer

Competitive salary and benefits commensurate with qualifications and experience.

Modern, well-equipped office and laboratory facilities on Abingdon Science Park.

Training and development opportunities in-line with the company’s goals and growth plans.

An exciting opportunity to help establish an early-stage biotech with ambitions to impact patients’ lives.

How to apply

Applications will be evaluated in the order that they are received, you are encouraged to apply as soon as possible.

Applications will close once the position is filled.

Quick apply

Refine Your Search

clinical research scientist jobs in oxford, eng

Scientist - Cell Biology

Research Assistant - Centralised National Virtual Clinic

Clinical Research Fellow

Senior Research Scientist I - Infectious Diseases

Principal Research Associate, Clinical Biomarker Laboratory, Flow Cytometry

Clinical Biospecimen Scientist - Single Sponsor Dedicated

Research Scientist – Autoimmune Research

Senior Research Associate, Bioanalytical & Molecular Assays

Principal Scientist, Bioanalytical & Molecular Assays

Specialist Biomedical Scientist (x2)

Research Assistant in neuron-astrocyte communication in neurodegeneration

Research Technician in Clinical Islet Isolation and Transplantation (Maternity Cover)

Senior Scientist, Analytical Development

Laboratory Operations Assistant

Scientist

Postdoctoral Researcher in Big Data for Cardiovascular Population Health

Senior Bioinformatician in Single-cell and Spatial Multiomics

Principal Scientist

Senior Biomedical Scientist

Scientist II

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