Key Responsibilities
Individual is expected to be a highly experienced scientist with a strong working knowledge of immuno-oncology and the drug-development process. They will be confident in designing and conducting experiments that enable the advancement of the Company’s pipeline through the functional validation of our ImmTAX molecules.
KEY RESPONSIBILITIES
Independently design and perform cell biology experiments to support the functional assessment of ImmTAX molecule screening through to candidate nomination in accordance with set timelines. Observe, interpret and respond to the results
Proactively contribute to internal cross-functional project / programme team meetings. Generate and communicate knowledge and data packages to solve complex problems and help inform go / no-go decisions
Understand and align with strategy within the therapeutic area and Research
Collaborate with colleagues to build a deep knowledge around targets and technologies of strategic interest to Immunocore.
Introduce new techniques/approaches that improve preclinical workflows
Maintain and increase technical knowledge in relevant fields through self-study, observation, attending relevant training courses
Contribute to peer reviewed publications and patents
Contribute to internal and external conferences
Maintain accurate records of all work and data generated by completing experiment write ups & electronic laboratory notebooks on time, following Company procedures
Ensure that laboratory equipment is operated in accordance with relevant protocols and/or SOPs and safety & risk guidelines; acting promptly to report any faults or problems to the relevant member of staff.
Operate in accordance with the Company’s Codes of Practices and Environment, Health and Safety (EHS) policies
PERSON SPECIFICATION
Experience & knowledge
Strong working knowledge and understanding of immunology and cell biology
Prior experience of testing potential therapeutic molecules in relevant systems
Highly experienced in a broad range of immunoassay techniques, including isolation of primary human immune cells and proficiency in functional assays and endpoints (measuring proliferation and cytokines, flow cytometry, ELISA etc.)
Experience with culturing human primary cells from patient samples
Capable in the genetic modification of cell lines and/or primary human immune cells. Evidence of using GM in vitro models to answer biological hypotheses.
Excellent written & oral communication skills
Education & qualifications
PhD or equivalent in Immunology, Pharmacology, Oncology, Molecular cell biology or similar discipline
3+ years’ experience of post-doctoral research in an academic or industrial setting
MSc degree or BSc degree with substantial role-specific equivalent research or industrial experience.
About the Company
Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.