Job Title: Senior Scientist; Protein and Cell Sciences
Location: Cambridge, UK
Salary: Competitive with excellent benefits!
Introduction to role:
Are you ready to turn recombinant protein design into therapies that change the way cancer is treated? In this laboratory-based role, you will deliver high-quality antigens that fuel our biologics discovery portfolio and help move promising ideas into the clinic. Your work will directly enable teams to evaluate novel modalities and make faster, better-informed decisions for patients.
As a Senior Scientist in Protein and Cell Sciences, you will design, express, purify and characterize recombinant proteins that underpin antibody discovery and other biologics programs. You will use modern computational tools alongside rigorous experimental methods to ensure the proteins you produce behave as intended. Can you see your experiments influencing cross-functional strategy in real time? This is the bench where that happens.
Accountabilities:
Protein Production: Express and purify recombinant proteins using bacterial and transient mammalian systems (E.coli, HEK, CHO), building robust, scalable methods and standard operating procedures that improve throughput and reproducibility.
Functional Characterization: Develop and deploy assays to monitor protein expression, function and quality (e.g. SDS-PAGE, analytical SEC, ELISA, cell based assays, OCTET), ensuring integrity and suitability for downstream applications.
Data, Documentation and Insight: Make detailed observations, analyze data and interpret results; maintain rigorous electronic laboratory notebooks and databases to create a reliable evidence base for decision-making.
Essential Skills/Experience:
Practical knowledge of developing and deploying assays to monitor/assess protein expression, function and quality (e.g. SDS-PAGE, analytical SEC, ELISA, cell based assays, OCTET).
Desirable Skills/Experience:
Why AstraZeneca:
Here, science meets bold collaboration to deliver meaningful outcomes for people living with cancer. You will learn from diverse experts who blend academic rigor with industrial scale, working with cutting-edge computational tools and rich data to push biologics forward. We bring unexpected teams into the same room to unleash inventive thinking, value kindness alongside ambition, and empower individuals to take smart risks—so your contribution at the bench connects to real change in the clinic.
So, what's next?
Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.
If you’re ready to craft high-impact recombinant proteins and see your science translate into therapies, step into this role and help shape the next wave of oncology biologics.
Where can I find out more?
Our Social Media,
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Date Posted
08-Jun-2026
Closing Date
21-Jun-2026
Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
