At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job Description
The ACE Regional Portfolio Strategy Lead owns and drives the integrated, cross-asset portfolio strategy across the ACE region, ensuring consistent translation of global strategy into actionable, regionally relevant execution guidance.
This role acts as the critical strategic bridge between Global and Country teams, enabling aligned scientific positioning, coordinated execution, and proactive portfolio management across affiliates in a complex and heterogeneous environment.
Key Responsibilities
1. Regional Portfolio Strategy Leadership
Own the ACE-level portfolio strategy across all assets and disease areas.
Translate global strategy into clear, prioritised, and actionable regional guidance to support consistent country execution (e.g., POA alignment).
Ensure coherent portfolio-wide scientific positioning across the region.
2. Strategic Integration & Execution Alignment
Drive alignment across Medical Affairs, Government Affairs, Public Affairs, and other cross-functional stakeholders.
Partner with ACE networks (e.g., CMD TA Leads, GMA Execution Lead) to ensure consistent and high-quality regional execution .
Enable best-practice sharing and adoption across affiliates to reduce variability in execution.
3. Above-Country Scientific & External Engagement
4. Portfolio Insights & Decision Support
Deliver portfolio-level insights, analysis, and recommendations to regional leadership.
Identify and monitor emerging regional risks, opportunities, and external trends .
Support proactive, data-driven regional decision-making in an increasingly complex portfolio.
5. Cross-Country Coordination & Issue Management
Drive coordinated, region-wide responses to scientific and strategic challenges affecting multiple affiliates.
Ensure early identification and mitigation of cross-country risks .
Improve speed and quality of decision-making by reducing fragmentation and reactive approaches.
Scope & Impact
Geography: ACE region (multi-country, heterogeneous access and policy landscape)
Portfolio: All assets across disease areas
Level: Enterprise/Regional (ED or SD level)
Impact:
Drives consistency in scientific messaging and execution across affiliates
Enhances strategic clarity and prioritisation at country level
Strengthens external influence and stakeholder alignment
Enables faster, proactive portfolio decision-making
Key Interfaces
Internal
Global Medical Affairs
ACE Medical Leadership (CMD TA Leads, affiliates)
Government Affairs / Public Affairs / GV&A
Commercial and cross-functional regional teams
GMA Execution Lead
External
Critical Capabilities & Experience
Technical / Functional
Deep understanding of portfolio strategy and lifecycle management
Strong expertise in Medical Affairs and scientific positioning
Experience with EMA label processes and regional policy environments
Leadership & Strategic Skills
Ability to operate at enterprise/portfolio level rather than single-asset focus
Strong strategic translation skills (global regional country)
Proven capability in cross-functional and matrix leadership
Skilled in navigating complexity and heterogeneity across markets
External Engagement
Experience engaging with above-country stakeholders and influencers
Strong understanding of health policy, access, and guideline ecosystems
Success Measures (Typical for Gilead Role Profiles)
Alignment and consistency of portfolio execution across ACE affiliates
Quality and impact of regional strategic guidance (POA alignment)
Effectiveness of cross-country risk identification and mitigation
Strength of external stakeholder engagement and influence
Contribution to regional leadership decision-making and outcomes
Why This Role is Critical
This role addresses a structural gap between global strategy and country execution , ensuring the ACE region can manage increasing portfolio complexity while maintaining consistency, speed, and strategic coherence.
Without it, execution remains fragmented, decision-making reactive, and opportunities for regional scale and influence underleveraged.
The role is based in UK – UK contract. We are pleased to share that Gilead’s Stockley Park and Holborn offices are planning to come together at a new London headquarters at 1 Triton Square, NW1, from approximately Q2 2027. Applicants should consider this planned location change when applying for this role. Gilead operates a flexible working policy, offering a balanced approach with two days of remote working and three days working onsite.
It is the policy of Gilead Sciences, Inc. and its subsidiaries and affiliates (collectively "Gilead" or the "Company") to recruit select and employ the most qualified persons available for positions throughout the Company. Except if otherwise provided by applicable law, all employment actions relating to issues such as compensation, benefits, transfers, layoffs, returns from layoffs, company-sponsored training, education assistance, social and recreational programs are administered on a non-discriminatory basis (i.e. without regard to protected characteristics or prohibited grounds, which may include an individual’s gender, race, color, national origin, ancestry, religion, creed, physical or mental disability, marital status, sexual orientation, medical condition, veteran status, and age, unless such protection is prohibited by federal, state, municipal, provincial, local or other applicable laws). Gilead also prohibits discrimination based on any other characteristics protected by applicable laws.
Please apply via the Internal Career Opportunities portal in Workday.
