Scientist Work, Jobs in Thornton, Fif (with Salaries)

Postdoctoral Scientist
University of Dundee —Dundee
- £37,174 - £45,413 a year
- Doctoral degree
- Communication skills
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- Full-time
- Hybrid work
- Doctoral degree
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- Annual leave
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- Doctoral degree
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Associate Director Climate Resilience and Adaptation
AECOM —Edinburgh
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AECOM —Edinburgh
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Yelp —Edinburgh
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- Full-time
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- AI
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Postdoctoral Scientist

University of Dundee -
Dundee

Apply Now

Job details

Fixed term contract
£37,174 - £45,413 a year
8 days ago

Qualifications

Biology
Doctoral degree
Multidisciplinary collaboration
Communication skills
Time management

Full job description

Closing date

Monday, 31 August 2026, 23:59

Salary

£37,174 - £45,413 per annum
Grade 7

Contract type

Fixed Term
mid-Jan 2027

Campus

City

Faculty/Directorate

Faculty of Life Sciences

Unit/Department

Centre for Targeted Protein Degradation

We are seeking an exceptional Structural Biologist / Molecular Biophysicist to join an interdisciplinary, crossinstitutional research team dedicated to developing an innovative new class of small molecules termed Phosphatase Targeting Chimeras (PhosTACs).

The appointed researcher will be based within the state-of-the-art laboratories of the University of Dundee's CeTPD (https://www.dundee.ac.uk/cetpd), and will focus on the structural and biophysical characterisation of protein-ligand interactions and protein-protein complexes relevant to the PhosTACs programme, to understand binding modes and structure-activity relationships (SAR) and guide the design of improved molecules. This is a broader and more independent role than a standard support post: the successful candidate will be expected to take increasing ownership of structural enablement of newly identified small-molecule binders, to drive structure-guided design decisions and to help lead this workstream across the collaboration.

This is a unique opportunity to gain experience in world-leading, collaborative and cutting-edge research in one of the hottest areas of modern translational chemical biology and drug discovery, within an academia-industry partnership with exciting prospects for the future.

Your priorities will include:

Characterising the binding of small-molecule bifunctional PhosTACs and their binding components to their target phosphatase and phospho-proteins components, using a range of structural and biophysical techniques including but not limited to X-ray crystallography, cryo-EM, NMR spectroscopy, and in-solution biophysical methods such as SPR, ITC and fluorescence-based assays
Designing constructs and expressing and purifying proteins to enable compound evaluation
Executing and optimising binding assays in vitro to profile novel compounds
Driving structure-guided design of PhosTACs by determining structure-activity relationships (SAR) in vitro, and taking a leading role in translating these into design recommendations for the wider team
Developing team science, working with colleagues across disciplines and institutions to enable breakthroughs
Presenting findings to the collaboration team and externally at international conferences

Who we're looking for:

A Ph.D. in structural biology, biophysics, biochemistry, chemical/molecular biology or a related discipline
Highly experienced in structural biology and biophysics, with an emphasis on structure-based drug design
Strong background in protein structure determination by X-ray crystallography, cryo-EM and/or NMR spectroscopy
Experience with biophysical techniques and assays to study protein-ligand binding and protein-protein interactions is strongly desired
Strong interpersonal, time management and communication skills
An open and collaborative approach to science
Capable of working in a diverse, cross-institutional team, but able to plan and work independently

For further information about this position please contact Professor Alessio Ciulli ([email protected])

To find out more about the Ciulli group or CeTPD, please visit the Website.

Apply Now

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scientist jobs in thornton, fif

Postdoctoral Scientist

Applied Scientist, Intelligent Talent Acquisition - Lead Generation & Detection Services

Lead Clinical Embryologist

Principal Water Quality Scientist/ Modeller

Senior Regulatory Toxicologist

Applied Scientist, Demand Tech, Amazon Ads

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Senior Data Scientist

Engineering Geologist

Senior Software Engineer - Machine Learning (Marketplace Dynamics) (Remote - United Kingdom)

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Senior/Principal Hydrogeologist

Data Scientist - Applied AI (Go-To-Market) 12 Months Fixed Term

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