Research Associate
The Trost Lab within the Division of Molecular & Cellular Function wish to appoint a laboratory-based Research Associate to characterise bacterial phagosomes in macrophages by state-of-the-art proteomics techniques using our recent flow-cytometry based isolation approach. This position is funded for 24 months with a start date between September-December 2026.
You will be responsible for:
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Isolation of primary murine macrophages and bone marrow-derived macrophages from mice.
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Infection of macrophages with Salmonella enterica spp. Typhimurium.
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Isolation of Salmonella vacuoles/phagosomes by flow cytometry.
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Sample preparation for proteomics and collaboration with our lab’s proteomics experts.
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Utilisation of our data analysis pipelines in R.
About You
We seek a talented and enthusiastic post-doctoral scientist with a background in infection biology or either microbiology, molecular immunology, biochemistry, or cell biology. You should demonstrate:
Essential Criteria
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Have, or be about to obtain, a relevant PhD (or equivalent)
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Extensive hands-on experience with infection of mammalian cells with bacterial pathogens.
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Excellent technical skills in core lab techniques and benchwork.
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Proven ability to use initiative to efficiently plan, optimise and progress project and communicate findings.
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At least one first author publication in an internationally recognized journal (or on repository).
Desirable Criteria
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Experience with Salmonella and the ability to make mutants.
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Experience with flow cytometry.
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Experience with macrophages.
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Proficient in handling and analysing large omics datasets using R.
Our benefits include:
Generous employer contribution pension
29 days annual leave plus bank holidays, along with Christmas closure
Ride to work and EV car scheme available
For more information, please see University of Manchester Benefits. You can also find information on our Flexible and Hybrid working here.
We are an open place of enquiry and challenge. We embrace and celebrate difference, diversity and debate, and we pride ourselves on being a place of education, learning and community where we are able, within the law, to question and test received wisdom, express new ideas and explore controversial or unpopular topics and opinions. Find out more from our Freedom of Speech Policy.
Enquiries about the role, shortlisting and interviews
Name: Matthias Trost
Email Address: [email protected]
General enquiries and administrative support
[email protected]
Technical and job portal support
https://jobseekersupport.jobtrain.co.uk/support/home
Applications close at midnight on the closing date.
Further particulars (with person specification) linked below.
