Associate structural Work, Jobs in Bilton, Nyk (with Salaries)

Research Associate in Structural and Mechanistic Enzymology of Bacteriophage
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- £37,694 a year
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13d
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Research Associate in Structural and Mechanistic Enzymology of Bacteriophage
University of York —University of York
To conduct research under the supervision of senior colleagues and to contribute to the production of research, in particular to:
£37,694 a year
13d

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associate structural jobs near bilton, nyk

Research Associate in Structural and Mechanistic Enzymology of Bacteriophage

University of York -
University of York

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Job details

Full-time
£37,694 a year
13 days ago

Qualifications

Biology
Doctoral degree
Engineering
Bachelor's degree
Construction experience
AI
Communication skills

Full job description

Department

The Department of Biology is recognised as one of the leading and most accomplished departments at York, with a global reputation for excellence in both teaching and research. We are committed to fostering a supportive environment where staff and students can thrive, contribute their best, and achieve their full potential. We take great pride in holding the Athena Swan Gold Award.

A postdoctoral position is available to investigate the structure and infection mechanisms of bacteriophage. The focus will be on engineering bacteriophage enzymes for altered tropism towards different bacterial receptors, assaying their activity by LC-MS/HPLC and biochemical assays, analysis by TEM/SEM, and structure determination by X-ray crystallography and cryo-EM. The successful candidate will join a collaborative and supportive environment in the Department of Biology, working closely with the Bayfield research group and the York Structural Biology Laboratory (YSBL).

Role

To conduct research under the supervision of senior colleagues and to contribute to the production of research, in particular to:

Engineer enzymes to confer novel functionalities
Assay enzyme activity using LC-MS/HPLC and biochemical assays
Determine the chemical mechanisms underlying enzyme activity
Determine enzyme structures using X-ray crystallography
Analyse biological samples using TEM and SEM

Skills, Experience & Qualification needed

Undergraduate degree in Chemistry
PhD in enzyme engineering, structural biology, biocatalysis and equivalent experience
Knowledge of protein-ligand complex structure determination by X-ray crystallography
Knowledge in enzyme engineering including mutant library construction
Knowledge in enzyme assaying by LC-MS and HPLC
Skills in generating structure- and AI-guided mutant libraries for altered enzyme specificity
Skills in LC-MS and HPLC-based enzyme activity assays, including cofactor-dependent enzymes
Skills in protein X-ray crystallography, including optimisation of protein-ligand complexes
Skills in analysing proteins and bacteriophage by TEM, SEM/STEM and cryo-EM
Familiarity with titering bacteriophage
Published in the field of enzyme engineering and protein structure determination
Demonstrated experience of characterising enzyme mechanisms and substrate specificity
Interest in and enthusiasm for research on the enzyme engineering
Highly developed communication skills to engage effectively with a wide ranging audience
Ability to develop research objectives, projects and proposals for own and joint research
Competency to conduct individual and collaborative research projects

When applying please upload a 2 page copy of your CV.

Interview date: August 2026

For informal enquiries: Please contact Dr Oliver Bayfield, [email protected]

The University strives to be diverse and inclusive – a place where we can ALL be ourselves.

We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University.

We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff. #EqualityatYork

As a Disability Confident employer, we will ensure that a fair and proportionate number of disabled applicants that meet the minimum (essential) criteria for each position will be offered an interview. Read more about the University of York’s commitments under the Disability Confident scheme.

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Research Associate in Structural and Mechanistic Enzymology of Bacteriophage

Associate Structural Engineer

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