Senior scientist, computational chemistry Work, Jobs in Chalgrove, Oxf (with Salaries)

Senior Scientist, Analytical Development
Replimune —Abingdon
- Full-time
- Doctoral degree
- Computer literacy
- Master's degree
Quick apply
9d
Senior Research Scientist
Milvus Advanced —Oxford
- £40,000 - £50,000 a year
- Full-time
- Doctoral degree
- In-person
- Communication skills
- Free parking
- Relocation assistance
Quick apply
7d
Senior Scientist
Genomics —Oxford
- Full-time
- Hybrid work
- Python
- Annual leave
Principal Scientist, Bioanalytical & Molecular Assays
Moderna, Inc. —Oxford
- Full-time
- Doctoral degree
- Master's degree
- Annual leave
PhD Programme Studentship
The Rosalind Franklin Institute —Harwell
- Full-time
- Data analysis skills
- Laboratory experience
- Maths
13d
Senior Postdoctoral Research Scientist in Immunology
University of Oxford —Oxford
- £49,119 - £65,336 a year
- Full-time
- Doctoral degree
- Communication skills
13d
Senior Bioinformatician in Single-cell and Spatial Multiomics
University of Oxford —Oxford
- £49,119 - £55,031 a year
- Full-time
- Doctoral degree
- Data analysis skills
- Machine learning
- Annual leave
Principal Scientist
LGC Group —Kidlington
- Full-time
- Microsoft Powerpoint
- Microsoft Word
- Doctoral degree
Quick apply
10d
Senior Director, Medicinal Chemistry
Vertex Pharmaceuticals —Oxford
- Full-time
- Organisational skills
- In-person
9d
ADME Scientist
Eurofins UK PSS —Abingdon
- Full-time
- Bachelor's degree
- No degree
- Communication skills
- Free parking
- Annual leave
Quick apply
2d
Junior Product Development Scientist
pladis —High Wycombe
- Full-time
- Employee assistance programme
- Employee discount
Senior AMO Physicist
Quantum Fabrix —Kidlington
- Full-time
- Doctoral degree
- CAD
- Project management
- Annual leave
Quick apply
Research Assistant
University of Oxford —Oxford
- £35,681 - £46,476 a year
- Full-time
- Data analysis skills
- Laboratory experience
- Travel
8d
Postdoctoral Researcher in Quanti...
The Rosalind Franklin Institute —Harwell
- £38,500 - £39,500 a year
- Full-time
- Doctoral degree
- Laboratory experience
- Organisational skills
- Free parking
- Annual leave
9d
Senior Researcher
University of Oxford —Oxford
- £49,119 - £65,336 a year
- Full-time
- Doctoral degree
- Machine learning
- Communication skills
13d
Senior Toxicologist
UK Health Security Agency —Chilton
- £44,148 - £50,121 a year
- Full-time
- Hybrid work
- Doctoral degree
- Data analysis skills
- Laboratory experience
14d
Senior Scientist I – Biocompatibility
Abbott Laboratories —Witney
- Full-time
- Microsoft Powerpoint
- Microsoft Word
- Microsoft Outlook
Senior Solutions Architect, Physical AI and Robotics at NVAITC
NVIDIA —Reading
- Full-time
- Doctoral degree
- Engineering
- English
Lab Manager – Molecular Immunology
University of Oxford —Oxford
- £39,242 - £47,779 a year
- School
Research Associate in Secondary I...
The Rosalind Franklin Institute —Harwell
- £38,500 - £39,500 a year
- Full-time
- Doctoral degree
- Leadership
- Free parking
- Annual leave

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Senior Scientist, Analytical Development

Replimune -
Abingdon

Quick apply

Job details

Full-time
9 days ago

Qualifications

Doctoral degree
Computer literacy
Master's degree
Statistical analysis
Bachelor's degree
Product development
Organisational skills
Communication skills

Full job description

Overview

Replimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient’s lives depend on it.

At Replimune, we live by our values:

United: We Collaborate for a Common Goal.

Audacious: We Are Bold.

Dedicated: We Give Our Full Commitment.

Candid: We Are Honest With Each Other.

People are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves.

Join us, as we reshape the future.

Summary of job description:

Sr. Scientist Analytical Development is responsible for developing, optimizing, qualifying, and validating analytical methods based on new and existing methodologies to qualitatively and quantitatively evaluate both drug substance and drug product, from preclinical through late phase clinical development. Analytical development supports drug substance/drug product release, process development, and characterization and/or stability testing of Replimune’s clinical material. In addition, coordination of analytical development and analysis work at CMOs/CROs will be a significant portion of the duties of the Sr. Scientist Analytical Development.

This position is based in our Milton Park location and typically has a 5-day on-site expectation.

Key responsibilities:

Manage the development, qualification and validation of analytical test methods and technology transfer in accordance with ICH and other regulatory guidances.
Support release and stability testing performed in house and at contract research organization (CRO), and directing good manufacturing practices (GMP) investigations including deviation root cause analyses, corrective action preventative action (CAPA), and out of specification (OOS).
Develop strategies for evaluating and implementing new technologies within Analytical Development.
Support process development, setting of specifications, and chemistry manufacturing and control (CMC) regulatory filings and responses.
Involved in daily workings of the group and actively participate in method troubleshooting and data analysis.

Other responsibilities:

Supervise the work of Assay Development Scientists or Technicians
Analytical Development (AD) representative for cross function meetings/projects with manufacturing, Quality Assurance (QA), Regulatory Affairs and external partners.
Provide AD review and approval of SOPs, risk assessments, protocols and reports.
Provide regular updates of AD group activities to the Chief Operating Officer and other Replimune senior management.

Educational requirements:

Education will be appropriate to specific job requirements. The following educational requirements are a minimum:

B.A or B.S. degree in a relevant biological science. M.S., Ph.D. or other post-graduate degree in biochemistry or related science is preferred

Experience and skill requirements:

Training and experience will be appropriate to specific job requirements. The following categories will be assessed in each case:

5-10 years industry experience, preferably in a cGMP Quality environment
Experience working in a GMP testing environment with an understanding of regulatory requirements and trends related to analytics and product development.
Thorough understanding of current regulatory requirements and practical experience of QC testing in support of cGMP operations
Ability to interface effectively with management and other groups or project teams
Computer processing literacy and experience in statistical analysis
Excellent verbal and written communication skills
Good organizational skills

About Replimune

Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com.

We are an Equal Opportunity Employer.

Quick apply

Refine Your Search

senior scientist, computational chemistry jobs in chalgrove, oxf

Senior Scientist, Analytical Development

Senior Research Scientist

Senior Scientist

Principal Scientist, Bioanalytical & Molecular Assays

PhD Programme Studentship

Senior Postdoctoral Research Scientist in Immunology

Senior Bioinformatician in Single-cell and Spatial Multiomics

Principal Scientist

Senior Director, Medicinal Chemistry

ADME Scientist

Junior Product Development Scientist

Senior AMO Physicist

Research Assistant

Postdoctoral Researcher in Quanti...

Senior Researcher

Senior Toxicologist

Senior Scientist I – Biocompatibility

Senior Solutions Architect, Physical AI and Robotics at NVAITC

Lab Manager – Molecular Immunology

Research Associate in Secondary I...

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