MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU):
The MRC PPU is one of the world's most renowned centres for research on protein phosphorylation and ubiquitylation (http://www.ppu.mrc.ac.uk/). Many world-leading researchers in the field of signal transduction have trained within the MRC PPU. The major aims of the MRC PPU are to advance understanding of the role of protein phosphorylation and ubiquitylation in cell regulation and human disease, to facilitate the development of drugs to treat diseases caused by abnormalities in phosphorylation, to generate reagents and improve technologies. A key remit of the MRC PPU is to train the next generation of scientists who will advance our understanding in this crucial area of medical research.
Faculty of Life Sciences (FLS):
The MRC PPU is based within the Faculty of Life Sciences at the University of Dundee, a world-class academic institution with a reputation for the excellence of its research, its high-quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the Faculty provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.
We are recruiting two highly motivated Research Technicians to participate in a new academic-industrial global initiative supported by the Michael J Fox Foundation for Parkinson's Research, aimed at accelerating the development of Parkinson's disease therapeutics. The project aims to explore and validate new therapeutic molecules modulating novel targets associated with Parkinson's disease. The postholder will be involved in in vivo mouse studies and proteomics characterizations, working closely with the other members of the research team. This exciting position enables further training in state-of-the-art methods through the course of the project and involves wider collaboration with other academic Institutions worldwide (Stanford University and KU Leuven) and Industry partners working in this area
The appointed post holders will be based in the laboratories of Professor Miratul Muqit and Professor Dario Alessi at the University of Dundee's MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU; http://www.ppu.mrc.ac.uk/).
- To undertake research in the relevant discipline area using the appropriate methods and/or
- To support the production of research reports and/or publications as required by the funding body or for dissemination to the wider academic community.
- To collaborate with research colleagues and support staff internally as appropriate to the
- To undertake any other duties relevant to the programme of research as
- For Grade 6 positions, the postholder will be expected to be able to work with minimal supervision, effectively plan own workload, and provide support and guidance to other members of the research team, as required.
- MSc in a relevant
- Strong hands-on experience in one or more of the following is essential: proteomics, organelle isolation, in vivo experiments; general biochemistry and cell biology techniques such as SDS-PAGE and immunoblotting techniques; Data analysis.
- Hands-on experience in experimental techniques and data analysis that are relevant to the
- Knowledge and interest in understanding pathways that are linked to neurodegeneration and Parkinson's
- Experience of working in a fast paced, ideally commercially-focused environment, and ability to manage competing deadlines and priorities are highly desirable.
- Ability to work in a team in a highly collaborative manner, embracing the principles of Open
- Excellent interpersonal and organisational
- Excellent knowledge of the English language is
- Experience in independent research
- Experience in multi-institutional and/or industry collaborations is highly
We are one of the UK's leading universities, internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Our purpose is to transform lives, locally and globally, which we do as a community of staff (Professional Services and academic Facultys), students and alumni. Professional Services directorates are key to delivering the University strategy and driving change across the University.
For further information about this position please contact Prof Miratul Muqit at [email protected] or prof. dario Alessi at [email protected]. To find out more about MRC PPU please visit https://www.ppu.mrc.ac.uk/
Commitment to DORA
The Faculty of Life Sciences has been fully committed to the principals of the San Francisco Declaration on Research Assessment (DORA) since 2013. In assessing applicants, we consider the scientific quality of their published research papers, but do not take into account where the papers were published and do not consider journal-based metrics, such as Journal Impact Factors.
As an internationally diverse institution, we welcome job applicants from all countries and nationalities. The Faculty of Life Sciences is proud to employ staff from over 40 different nations.
The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.
