Principal scientist Work, Jobs in Eng (with Salaries)

Principal Data Scientist
CoMind —London
- £152,000 - £190,000 a year
- Full-time
- IT
- AI
- Leadership
- Employee discount
11d
Principal Scientist/Senior Principal Scientist – Statistical Genetics
GlaxoSmithKline —Stevenage
- Full-time
- Hybrid work
- Doctoral degree
- Machine learning
- In-person
13d
Principal Scientist, Bioanalytical & Molecular Assays
Moderna, Inc. —Oxford
- Full-time
- Doctoral degree
- Master's degree
- Annual leave
12d
Principal Scientist, Clinical Research - Remote UK
Leica Biosystems —Newcastle upon Tyne
- Full-time
- Remote
- Doctoral degree
- Master's degree
- Bachelor's degree
Senior or Principal Soil Scientist
AtkinsRéalis —Bristol
- Full-time
- Hybrid work
- Engineering
- Travel
- Communication skills
Principal Scientist, Inflammation Research
Gilead Sciences —Oxford
- Full-time
- Doctoral degree
- Communication skills
Principal Scientist (In Vitro DMPK)
Pharmaron —Hoddesdon
- Master's degree
- Bachelor's degree
- Leadership
Quick apply
Senior Principal Scientist / Director – Computational Chemistry (IDD)
Pharmaron —Hoddesdon
- Doctoral degree
- AI
- Leadership
Quick apply
MRI Principal Clinical Scientist
University College London Hospitals NHS Foundation Trust —London
- £75,328 - £86,114 a year
- Full-time
- University
- Leadership
Principal Scientist Immunoassay
Resolian —Fordham
- Full-time
Principal Scientist I, Translational Medicine Lab
Immunocore —Oxford
- Full-time
- Doctoral degree
- Supervising experience
- Mentoring
Protein Scientist
Substrate Bio —London
- Full-time
- Laboratory experience
- Maintenance
- AI
- Annual leave
Quick apply
Principal / Lead Separation Scientist (Chemistry)
Sygnature Discovery —Nottingham
- Full-time
- Doctoral degree
- Master's degree
- Machine learning
- Annual leave
- Employee assistance programme
Quick apply
Principal Scientist, Immunogenicity and Ligand Binding Assays
Moderna, Inc. —Oxford
- Full-time
- Doctoral degree
- Data analysis skills
- Master's degree
- Annual leave
11d
Chemistry Principal Scientist
Substrate Bio —London
- Full-time
- Hybrid work
- Doctoral degree
- AI
- Annual leave
Quick apply
Principal Applied Data Scientist
LSEG (London Stock Exchange Group) —London
- Full-time
- Azure
- Computer Science
- DevOps
Principal Data Scientist
Lendable —London
- Full-time
- Hybrid work
- Management
- SQL
- Machine learning
- Referral programme
Associate Principal Scientist (In Vivo Pharmacology) - Kidney Disease/Inflammation/Metabolic Disease
Sygnature Discovery —Nottingham
- Full-time
- Doctoral degree
- Master's degree
- Bachelor's degree
- Annual leave
- Employee assistance programme
Quick apply
Principal Data Scientist
Sky —London
- Full-time
- Hybrid work
- SQL
- Machine learning
- AI
6d
Principal Data Scientist
AWTG —London
- Machine learning
- AI
- Leadership

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principal scientist jobs near eng

Principal Data Scientist

CoMind -
London

Apply Now

Job details

Full-time
£152,000 - £190,000 a year
11 days ago

Benefits

Private dental insurance
Unlimited paid holidays
Company pension
Employee discount

Qualifications

Signal processing
Physiology knowledge
IT
Data science
AI
Leadership
FDA regulations

Full job description

At CoMind, we are developing a non-invasive neuromonitoring technology that will result in a new era of clinical brain monitoring. In joining us, you will be helping to create cutting-edge technologies that will improve how we diagnose and treat brain disorders, ultimately improving and saving the lives of patients across the world.

The Role:

The Data Science team at CoMind develops the algorithms and machine learning systems that transform raw optical interference signals from CoMind One into continuous, clinically meaningful measurements of cerebral blood flow, intracranial pressure, and autoregulation. Working at the frontier of photonics, physiology, and applied ML, the team's work directly determines what CoMind One can measure, how accurately, and under what clinical conditions.

As Principal Data Scientist, you will be the technical authority for CoMind's data science function, setting methodological direction for signal extraction and ML modelling, personally driving the most complex and highest-impact problems, and providing expert guidance across the team. This is a senior individual contributor role: you will not manage people directly, but your technical leadership will shape how the entire team approaches its most challenging problems. You will work closely with R&D, Clinical, and Software Engineering.

At CoMind, all team members work at least 4 days per week from our new Kings Cross offices, plus a flexible work-from-home day.

Responsibilities:

Own the technical direction for signal processing and ML model development on CoMind One, defining approaches, architectures, and evaluation frameworks that set the standard for the team
Lead the development and validation of the most complex data science components, from novel algorithm design through to evidence generation for regulatory submissions
Act as the primary technical reviewer and expert resource across the data science team, setting the bar for methodological rigour, reproducibility, and scientific integrity
Drive the design and execution of data collection and labelling strategies with Clinical teams, including ground truth definition, dataset governance, and performance benchmarking
Contribute to CoMind's IP and publication strategy, authoring and reviewing technical papers, patent applications, and regulatory documents
Represent the data science function in cross-functional technical forums, architecture reviews, and external scientific and clinical engagements
Identify and introduce new methods, tools, and approaches that advance CoMind's signal extraction and ML capabilities
AI is fundamental to our culture. It's not just a tool, but a core part of how we work, collaborate, and innovate. We expect all team members to embrace AI in their daily work and continuously find new ways to use it effectively.

Skills & Experience:

15+ years of experience in data science, ML, or applied research, with a strong track record of independent technical leadership on complex, ambiguous problems
Deep expertise in time-series signal processing and physiological or biomedical ML, including hands-on experience developing and validating models on noisy, real-world physiological data
Demonstrated ability to take algorithmic work from research through to production-quality, validated implementation
Experience in a regulated industry (medical devices, diagnostics, pharma, or similar), with familiarity with algorithm validation and documentation requirements for software as a medical device
Strong record of scientific output: publications, patents, or equivalent evidence of original technical contribution and domain authority

Nice to Have

Background in neuroscience, neuromonitoring, neurophotonics, and/or cerebrovascular physiology
Experience with optical signal processing - e.g. LiDAR, pulse oximetry, NIRS, laser doppler flowmetry, or related technologies
Familiarity with FDA regulatory pathways for AI/ML-based medical devices

Benefits:

Company equity plan so all employees share in the success of the company
Salary-sacrifice pension scheme
Private medical, dental and vision insurance (medical history disregarded)
Group life assurance at 4x annual income
Comprehensive mental health support, including unlimited access to 1:1 sessions with trained professionals
Unlimited holiday allowance (+ bank holidays) and one week of remote working per quarter
Lunch voucher (£10) every day for JustEat and free dinner on those days where you need to work later
Twice weekly deliveries of fresh fruit and an extensive selection of snacks and drinks
YuLife subscription, allowing you to turn your daily steps and meditation into discounts at a range of stores
Access to Udemy for upskilling and professional development.

Compensation Range: £152K - £190K

Apply Now

Refine Your Search

principal scientist jobs in eng

Principal Data Scientist

Principal Scientist/Senior Principal Scientist – Statistical Genetics

Principal Scientist, Bioanalytical & Molecular Assays

Principal Scientist, Clinical Research - Remote UK

Senior or Principal Soil Scientist

Principal Scientist, Inflammation Research

Principal Scientist (In Vitro DMPK)

Senior Principal Scientist / Director – Computational Chemistry (IDD)

MRI Principal Clinical Scientist

Principal Scientist Immunoassay

Principal Scientist I, Translational Medicine Lab

Protein Scientist

Principal / Lead Separation Scientist (Chemistry)

Principal Scientist, Immunogenicity and Ligand Binding Assays

Chemistry Principal Scientist

Principal Applied Data Scientist

Principal Data Scientist

Associate Principal Scientist (In Vivo Pharmacology) - Kidney Disease/Inflammation/Metabolic Disease

Principal Data Scientist

Principal Data Scientist

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