Ref Number
B02-11147
Professional Expertise
Laboratory Technical and Lab Support
Department
School of Life & Medical Sciences (B02)
Location
London
Working Pattern
Full time
Salary
£31,904-£36,433
Contract Type
Fixed-term
Working Type
On site
Available for Secondment
No
Closing Date
04-Sept-2026
The UCL Cancer Institute is the hub for cancer research at University College London, one of the World's leading universities. The Institute brings together over 400 talented scientists working to translate research discoveries into kinder, more effective therapies for cancer patients. In particular, it fosters links between basic cancer researchers across biomedicine and with the clinical activities of our four partner hospital trusts, known as UCL Partners (University College London Hospital NHS Foundation Trust, Great Ormond Street Hospital for Children NHS Trust, the Royal Free Hampstead NHS Trust, and Moorfields Eye Hospital NHS Foundation Trust), as well as the London School of Pharmacy and Cancer Research UK. Further Information about the UCL Cancer Institute can be found on our website https://www.ucl.ac.uk/cancer/.
A major focus of Dr. Roddie’s UCL Translation Team at the UCL Cancer Institute is the manipulation of T-cells for therapeutic applications. The main purpose of this position is to genetically modify CAR T cells using molecular biology and gene editing approaches, including CRISPR-mediated gene knockout, to investigate and enhance CAR T-cell function. The role involves performing a range of molecular and cellular assays to assess CAR T-cell performance, including their proliferation, cytotoxicity, persistence, phenotype, and other functional characteristics. Training in relevant techniques will be provided.
The successful candidate will be part of a collaborative group of scientists and will be expected to actively assist and participate in all aspects of the research, as well as in the basic maintenance of the laboratory.
This is position will be funded for 6 months in the first instance, with the possibility of extension.
Applications should include a CV and a Cover Letter: In the Cover Letter, please provide evidence of the essential and desirable criteria in the Person Specification part of the Job Description. (By including a Cover Letter, you can leave blank the 'Why you have applied for this role' field in the application form, which is limited in the number of characters it will allow.)
The job does not meet the eligibility requirements for a Skilled Worker Visa certificate of sponsorship under UK Visas and Immigration legislation. Therefore, UCL will not be able to sponsor individuals who require the right to work in the UK to carry out this role.
You will hold a degree in Biological Sciences or a related discipline and have experience in aseptic cell culture and routine molecular biology techniques. An interest in immunotherapy, particularly CAR T-cell research, would be advantageous.
You will be highly organised, with excellent attention to detail and record-keeping skills, and the ability to follow protocols accurately while managing competing priorities.
The successful candidate will be a motivated and collaborative team player with a commitment to high-quality research, continuous learning, and working effectively with colleagues from diverse backgrounds. Experience of molecular cloning, nucleic acid extraction, flow cytometry, or a postgraduate qualification would be beneficial.
As well as the exciting opportunities this role presents we also offer some great benefits some of which are below
- 41 Days holiday (including 27 days annual leave 8 bank holiday and 6 closure days)
- Defined benefit career average revalued earnings pension scheme (CARE)
- Cycle to work scheme and season ticket loan
- On-Site nursery
- On-site gym Enhanced maternity, paternity and adoption pay
- Employee assistance programme
- Staff Support Service Discounted medical insurance
For rewards and benefits at UCL please visit:
Staff Benefits | UCL People & Culture - UCL – University College London
As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women.
You can read more about our commitment to Equality, Diversity and Inclusion here:
Equality, Diversity & Inclusion: Think differently, do differently. | Office of the President and Provost (Equality, Diversity & Inclusion) - UCL – University College London
