Principal scientist Work, Jobs in London (with Salaries)

Principal Data Scientist
CoMind —London
- £152,000 - £190,000 a year
- Full-time
- IT
- AI
- Leadership
- Employee discount
Head of Data Science (Principal Data Scientist)
Guy's and St Thomas' NHS Foundation Trust —London
- £88,250 - £100,355 a year
- Full-time
- Doctoral degree
- Master's degree
- SQL
11d
Principal Data Scientist
National Westminster Bank PLC —London
- Full-time
- Hybrid work
- Data analysis skills
- Machine learning
- Leadership
- Annual leave
16h
Principal Data Scientist | Media Measurement (MM)
NielsenIQ —London
- £90,000 - £112,000 a year
- Full-time
- Hybrid work
- Doctoral degree
- Master's degree
- AI
- Employee assistance programme
Quick apply
1d
Principal Data Scientist
Sky —London
- Full-time
- Hybrid work
- SQL
- Machine learning
- AI
Principal Data Scientist
Hiscox —London
- Full-time
- Master's degree
- SQL
- Bachelor's degree
Principal Data Scientist
marshmallow —London
- Full-time
- Hybrid work
- Machine learning
- AI
- Communication skills
Principal Data Scientist
AWTG —London
- Machine learning
- AI
- Leadership
Principal Applied Data Scientist
London Stock Exchange Group —London
- Full-time
- Azure
- Computer Science
- DevOps
Data Scientist - Principal
Product Madness —London
- Full-time
- Azure
- Doctoral degree
- Computer Science
Functional Genomics Scientist
Substrate Bio —London
- Full-time
- Doctoral degree
- Laboratory experience
- Maintenance
- Annual leave
Quick apply
Principal Water Quality Scientist/ Modeller
AECOM —Croydon
- Full-time
- Hybrid work
- Master's degree
- Project management
- Scripting
Principal Data Scientist
Faculty —London
- Full-time
- Hybrid work
- Management
- Machine learning
- Mentoring
- Annual leave
Senior Researcher
Nesta —London
- £50,700 - £67,800 a year
- Hybrid work
- Master's degree
- Analysis skills
- Bachelor's degree
- Annual leave
1d
Principal Data Scientist I
RELX —London
- Full-time
- Machine learning
Director, Preclinical External Innovation
LifeArc —London
- Full-time
- Doctoral degree
- Leadership
- Communication skills
- Annual leave
Principal Scientist (In Vitro DMPK)
Pharmaron —Hoddesdon
- Master's degree
- Bachelor's degree
- Leadership
Molecular Characterisation Scientist, Biologics
Substrate Bio —London
- Full-time
- Doctoral degree
- Laboratory experience
- Master's degree
- Annual leave
Quick apply
8d
Principal Data Scientist and Machine Learning Researcher (eDV)
Frontier Resourcing —London
- Full-time
- Hybrid work
- Azure
- Doctoral degree
- Master's degree
Quick apply
Principal Biostatistician (R/Rshiny - EMEA BASED)
サイネオス・ヘルス —London
- Doctoral degree
- English
- Machine learning

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Principal Data Scientist

CoMind -
London

Apply Now

Job details

Full-time
£152,000 - £190,000 a year

Benefits

Private dental insurance
Unlimited paid holidays
Company pension
Employee discount

Qualifications

Signal processing
Physiology knowledge
IT
Data science
AI
Leadership
FDA regulations

Full job description

At CoMind, we are developing a non-invasive neuromonitoring technology that will result in a new era of clinical brain monitoring. In joining us, you will be helping to create cutting-edge technologies that will improve how we diagnose and treat brain disorders, ultimately improving and saving the lives of patients across the world.

The Role:

The Data Science team at CoMind develops the algorithms and machine learning systems that transform raw optical interference signals from CoMind One into continuous, clinically meaningful measurements of cerebral blood flow, intracranial pressure, and autoregulation. Working at the frontier of photonics, physiology, and applied ML, the team's work directly determines what CoMind One can measure, how accurately, and under what clinical conditions.

As Principal Data Scientist, you will be the technical authority for CoMind's data science function, setting methodological direction for signal extraction and ML modelling, personally driving the most complex and highest-impact problems, and providing expert guidance across the team. This is a senior individual contributor role: you will not manage people directly, but your technical leadership will shape how the entire team approaches its most challenging problems. You will work closely with R&D, Clinical, and Software Engineering.

At CoMind, all team members work at least 4 days per week from our new Kings Cross offices, plus a flexible work-from-home day.

Responsibilities:

Own the technical direction for signal processing and ML model development on CoMind One, defining approaches, architectures, and evaluation frameworks that set the standard for the team
Lead the development and validation of the most complex data science components, from novel algorithm design through to evidence generation for regulatory submissions
Act as the primary technical reviewer and expert resource across the data science team, setting the bar for methodological rigour, reproducibility, and scientific integrity
Drive the design and execution of data collection and labelling strategies with Clinical teams, including ground truth definition, dataset governance, and performance benchmarking
Contribute to CoMind's IP and publication strategy, authoring and reviewing technical papers, patent applications, and regulatory documents
Represent the data science function in cross-functional technical forums, architecture reviews, and external scientific and clinical engagements
Identify and introduce new methods, tools, and approaches that advance CoMind's signal extraction and ML capabilities
AI is fundamental to our culture. It's not just a tool, but a core part of how we work, collaborate, and innovate. We expect all team members to embrace AI in their daily work and continuously find new ways to use it effectively.

Skills & Experience:

15+ years of experience in data science, ML, or applied research, with a strong track record of independent technical leadership on complex, ambiguous problems
Deep expertise in time-series signal processing and physiological or biomedical ML, including hands-on experience developing and validating models on noisy, real-world physiological data
Demonstrated ability to take algorithmic work from research through to production-quality, validated implementation
Experience in a regulated industry (medical devices, diagnostics, pharma, or similar), with familiarity with algorithm validation and documentation requirements for software as a medical device
Strong record of scientific output: publications, patents, or equivalent evidence of original technical contribution and domain authority

Nice to Have

Background in neuroscience, neuromonitoring, neurophotonics, and/or cerebrovascular physiology
Experience with optical signal processing - e.g. LiDAR, pulse oximetry, NIRS, laser doppler flowmetry, or related technologies
Familiarity with FDA regulatory pathways for AI/ML-based medical devices

Benefits:

Company equity plan so all employees share in the success of the company
Salary-sacrifice pension scheme
Private medical, dental and vision insurance (medical history disregarded)
Group life assurance at 4x annual income
Comprehensive mental health support, including unlimited access to 1:1 sessions with trained professionals
Unlimited holiday allowance (+ bank holidays) and one week of remote working per quarter
Lunch voucher (£10) every day for JustEat and free dinner on those days where you need to work later
Twice weekly deliveries of fresh fruit and an extensive selection of snacks and drinks
YuLife subscription, allowing you to turn your daily steps and meditation into discounts at a range of stores
Access to Udemy for upskilling and professional development.

Compensation Range: £152K - £190K

Apply Now

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principal scientist jobs in london

Principal Data Scientist

Head of Data Science (Principal Data Scientist)

Principal Data Scientist

Principal Data Scientist | Media Measurement (MM)

Principal Data Scientist

Principal Data Scientist

Principal Data Scientist

Principal Data Scientist

Principal Applied Data Scientist

Data Scientist - Principal

Functional Genomics Scientist

Principal Water Quality Scientist/ Modeller

Principal Data Scientist

Senior Researcher

Principal Data Scientist I

Director, Preclinical External Innovation

Principal Scientist (In Vitro DMPK)

Molecular Characterisation Scientist, Biologics

Principal Data Scientist and Machine Learning Researcher (eDV)

Principal Biostatistician (R/Rshiny - EMEA BASED)

I want to receive the latest job alerts for principal scientist in london

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