Senior principal scientist Work, Jobs in Much Hadham, Hrt (with Salaries)

Senior Principal Scientist / Director – Computational Chemistry (IDD)
Pharmaron —Hoddesdon
- Remote
- Doctoral degree
- AI
- Leadership
Senior Principal Scientist, Clinical Biomarkers
Ipsen Innovation (SAS) —London
- Full-time
- Doctoral degree
- English
Senior / Principal Scientist - Aptamer Biosensing
Stealth Deep Tech —London
- £50,000 - £80,000 a year
- Full-time
- Doctoral degree
- In-person
Quick apply
5d
Principal Machine Learning Engineer (Live Sports Insights)
Sky —London
- Full-time
- Hybrid work
- Machine learning
- Mentoring
- Leadership
Principal Data Scientist
CoMind —London
- £136,000 - £190,000 a year
- Full-time
- IT
- AI
- Leadership
- Employee discount
Senior/Principal Hydrogeologist
AECOM —Cambridge
- Full-time
- Hybrid work
- Master's degree
- Bachelor's degree
Principal Data Scientist – Precision Biomarkers in Skin Health
Mitra Bio —London
- Hybrid work
- Doctoral degree
- Master's degree
- Communication skills
6d
Senior Principal AI Engineer
Synapri —London
- £90,000 - £120,000 a year
- Hybrid work
- Azure
- AWS
- Presentation skills
Chemistry Principal Scientist
Substrate Bio —London
- Full-time
- Hybrid work
- Doctoral degree
- AI
- Annual leave
Quick apply
Senior Researcher
Nesta —London
- £50,700 - £67,800 a year
- Hybrid work
- Master's degree
- Analysis skills
- Bachelor's degree
- Annual leave
11d
MRI Principal Clinical Scientist
University College London Hospitals NHS Foundation Trust —London
- £75,328 - £86,114 a year
- Full-time
- University
- Leadership
Principal Hydrologist
AECOM —St Albans
- Full-time
- Hybrid work
- Engineering
- Data analysis skills
- Master's degree
Principal Data Scientist
marshmallow —London
- Full-time
- Hybrid work
- Machine learning
- AI
- Communication skills
Principal, Sales Enablement - 886
Quantinuum —London
- Full-time
- Hybrid work
- Sales
- Continuous improvement
- Annual leave
Principal Water Quality Scientist/ Modeller
AECOM —Cambridge
- Full-time
- Hybrid work
- Master's degree
- Project management
- Scripting
Molecular Characterisation Scientist, Biologics
Substrate Bio —London
- Full-time
- Doctoral degree
- Laboratory experience
- Master's degree
- Annual leave
Quick apply
Senior / Principal Civil 3D Modeller
AECOM —London
- Full-time
- Hybrid work
- AutoCAD
- Civil engineering
- Engineering
Data Scientist - Principal
Product Madness —London
- Full-time
- Azure
- Doctoral degree
- Computer Science
Protein Production Scientist, Biologics
Substrate Bio —London
- Full-time
- Doctoral degree
- Master's degree
- Supervising experience
- Annual leave
Quick apply
Principal Product Manager
Gigaton —London
- £100,000 - £130,000 a year
- Full-time
- Hybrid work
- Travel
- AI
Quick apply

I want to receive the latest job alerts for senior principal scientist in much hadham, hrt

By signing in to your account, you agree to SimplyHired's Terms of Service and consent to our Cookie and Privacy Policy.

Explore jobs in more locations

senior principal scientist jobs near much hadham, hrt

Senior Principal Scientist / Director – Computational Chemistry (IDD)

Pharmaron -
Hoddesdon

Apply Now

Job details

Permanent

Qualifications

Doctoral degree
AI
Leadership
Communication skills

Full job description

Job Introduction

Senior Principal Scientist / Director – Computational Chemistry (IDD)

Location: UK – Remote

About Pharmaron

Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the UK, US, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services.

We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers. To learn more, visit www.pharmaron.com.

Pharmaron is looking for a Senior Principal Scientist / Director – Computational Chemistry to lead on the design and optimisation of multi-modality ligands within our Integrated Drug Discovery programmes and help shape our Computational Sciences capability.

This is a senior role requiring scientific excellence, and client engagement to drive integrated, multi-modality drug discovery programmes.

The Integrated Drug Discovery (IDD) Services group at Pharmaron is responsible for leading and delivering drug discovery projects for our client partners. The team comprises scientific expertise and strategic leadership across medicinal chemistry, CADD, biology, DMPK and translational science. Combined with Pharmaron’s global research capabilities, we design and deliver integrated programmes from target identification and hit finding, through to IND filing. Working closely with our partners, we define strategy, coordinate execution across teams and, with an AI enabled accelerated Design–Make–Test–Analyse cycle, support the progression of projects and innovative medicines towards the clinic.

The Role

Lead Computational Sciences design strategy across a diverse portfolio of discovery projects from hit expansion through lead optimisation. Design, evaluate, and prioritize molecules for synthesis using a complete suite of computational tools
Provide scientific leadership to multidisciplinary project teams from hit-finding to candidate selection
Drive the application of modern CADD approaches (AI/ML, SBDD, cheminformatic) across small molecule and other modalities
Build and enhance computational infrastructure, tools and capabilities
Collaborate closely with global Computational Chemistry teams and cross-functional stakeholders
Build and strengthen client relationships, supporting business growth and long-term collaborations
Contribute to departmental strategy, innovation, capability development and business proposals
Represent Pharmaron externally, enhancing reputation within the Computational Sciences and broader drug discovery communities

About You

PhD in Computational Chemistry, Theoretical Chemistry, Molecular Modelling or related discipline
10+ years’ experience in computational drug discovery (Pharma, Biotech or CRO)
Proven track record delivering impact across drug discovery pipelines and key milestones
Expertise across CADD approaches, including SBDD, AI/ML and cheminformatics
Experience working across modalities (small molecules, peptides, biologics, emerging platforms)
Strong publication and/or patent record
Demonstrated experience leading multidisciplinary teams and external collaborations
Excellent communication skills

Key Skills

Deep knowledge of computational chemistry in drug discovery
Strong understanding of medicinal chemistry, biology and DMPK integration
Excellent communication and stakeholder influencing skills
Ability to manage multiple complex programmes in parallel

Key Attributes

Strategic thinker with the ability to translate vision into execution
Inspirational leader and team developer
Collaborative, adaptable and culturally aware
Results-driven with strong client focus
Passionate about innovation, continuous learning and scientific excellence

Why Join Pharmaron?

Lead cutting-edge computational science within a global CRO
Influence strategy, capability build and scientific direction
Work on diverse, high-impact discovery programmes
Collaborate with world-class global teams

If you're ready to take a leadership role in advancing cheminformatics and computational chemistry, we’d love to hear from you.

Salary Competitive
Frequency Annual
Job Reference ukpharmaron/TP/141/688
Contract Type Permanent Contract
Closing Date No expiry date
Job Category Scientific (CADD)
Division Drug Discovery
Location Hoddesdon, United Kingdom
Posted on 11 June, 2026

Apply Now

Refine Your Search

senior principal scientist jobs in much hadham, hrt

Senior Principal Scientist / Director – Computational Chemistry (IDD)

Senior Principal Scientist, Clinical Biomarkers

Senior / Principal Scientist - Aptamer Biosensing

Principal Machine Learning Engineer (Live Sports Insights)

Principal Data Scientist

Senior/Principal Hydrogeologist

Principal Data Scientist – Precision Biomarkers in Skin Health

Senior Principal AI Engineer

Chemistry Principal Scientist

Senior Researcher

MRI Principal Clinical Scientist

Principal Hydrologist

Principal Data Scientist

Principal, Sales Enablement - 886

Principal Water Quality Scientist/ Modeller

Molecular Characterisation Scientist, Biologics

Senior / Principal Civil 3D Modeller

Data Scientist - Principal

Protein Production Scientist, Biologics

Principal Product Manager

I want to receive the latest job alerts for senior principal scientist in much hadham, hrt

Related Searches

Explore jobs in more locations

Job Introduction

Jobseeker tools

Employer Tools

Browse

Stay Connected