Document specialist Work, Jobs in Cardiff, Crf (with Salaries)

Principal Scientist
Simbec-Orion —Merthyr Tydfil
- Full-time
- Doctoral degree
- Master's degree
- Business development
Commercial Contract Specialist
Oxford Instruments plc —Bristol
- Bachelor's degree
- Mentoring
- Contracts
- Annual leave
Consultant Cardiologist with an interest in Interventional Cardiology
Cardiff and Vale University Health Board —Cardiff
- £114,099 - £166,585 a year
- Full-time
- Hospital
- Research
- Teaching
8h
Bid Co-ordinator
Stride Treglown —Bristol
- Full-time
- Microsoft Powerpoint
- Microsoft Word
- Organisational skills
Securities Operations Services Specialist
Computershare —Bristol
- Full-time
- Hybrid work
- Analysis skills
- Work from home
14d
Solution Architect
Amentum —Cardiff
- Full-time
- System design
- Analysis skills
- IT
- Employee assistance programme
High Intensity Psychological Therapist
Cardiff and Vale University Health Board —Cardiff
- £50,129 - £57,365 a year
- Full-time
- Patient care
- Teaching
Cyber Security Vulnerability Manager
Digital Health and Care Wales —Cardiff
- £50,129 - £57,365 a year
- Full-time
- Training & development
- Leadership
- Annual leave
1d
CAD Technician
AmcoGiffen —Pontyclun
- £35,000 - £45,000 a year
- Full-time
- Civil engineering
- Engineering
- Communication skills
- Annual leave
Quick apply
7d
Clinical Psychologist
Velindre Cancer Centre —Cardiff
- £50,129 - £57,365 a year
- Part-time
- University
- Patient care
8h
Consultant Social Worker (IFSS)
Rhondda Cynon Taf —Rhondda Cynon Taff
- £52,413 a year
- Full-time
- Experience working with children
- Training & development
4d
Principal Marine Surveyor - Plan Approval
Maritime and Coastguard Agency —Cardiff
- £63,645 a year
- Part-time
- Hybrid work
- Master's degree
- Presentation skills
- Continuous improvement
- Annual leave
- Employee assistance programme
1d
Costs Lawyer/Draftsman - Personal Injury
Redkite Law —Cardiff
- Full-time
- Travel
- Communication skills
- Annual leave
Quick apply
14d
Locum Consultant in Intensive Care Medicine
Cardiff and Vale University Health Board —Cardiff
- £125,509 a year
- Full-time
- ICU experience
6d
Site Service Engineer
Rubix —Cardiff
- Full-time
- Maintenance
12d
Advanced Practitioner Radiographer - Head and Neck
Velindre Cancer Centre —Cardiff
- £50,129 - £57,365 a year
- Part-time
- University
- Patient care
8d
Heart Failure Service Clinical Nurse Specialist Lead
Cardiff and Vale University Health Board —Cardiff
- £58,379 - £65,723 a year
- Full-time
- Management
- Hospital
- Continuous improvement
7d
National Rental Driver
NRG Riverside —Newport
- £36,050 a year
- Overtime
- Customer service
- Free parking
- Annual leave
Quick apply
Fire Safety Team Leader
BRC Jobs —Newport
- £46,716.47 a year
- Full-time
- Engineering
- Team management
- Budgeting
- Annual leave
- Referral programme
Quick apply
15h
Senior Automation Engineer
Gavik Technology and Engineering Solutions —Blackwood
- £4,250 - £5,000 a month
- Full-time
- Programmable logic controllers
- Mentoring
- In-person
- Free parking
Quick apply

I want to receive the latest job alerts for document specialist in cardiff, crf

By signing in to your account, you agree to SimplyHired's Terms of Service and consent to our Cookie and Privacy Policy.

Principal Scientist

Simbec-Orion -
Merthyr Tydfil

Apply Now

Job details

Permanent | Full-time

Qualifications

GLP
Doctoral degree
Analytical chemistry
Stakeholder liaison
Mentoring junior staff
Master's degree
Business development
Continuous improvement
Quality control
Mentoring
Conversion optimisation
Clinical trials
Good Clinical Practice (GCP)
Project management experience
Communication skills
Good Clinical Practice (ICH-GCP) guidelines

Full job description

Our Mission:

Simbec-Orion is a responsive and agile full-service CRO, with wide therapeutic experience and specialist expertise in clinical pharmacology, oncology and rare diseases. Perfectly structured, we provide full-service clinical development solutions for small and mid-size drug developers – headed up by a centralised leadership team.

With a focus on tailormade and scalable solutions, we’ll adapt our delivery style, communications and operations to suit the demands of the project, helping clients achieve their clinical and commercial objectives. Because our goal is the same as theirs; to improve patients’ lives.

The Role:

We are seeking a Principal Scientist with advanced expertise in LC-MS/MS to join our Laboratory Services team as a technical Subject Matter Expert. You will lead the development, validation, and application of LC-MS/MS methods for bioanalytical studies, ensuring all activities are delivered in compliance with GCP, GLP, and/or GMP standards. The role requires deep technical knowledge of mass spectrometry, including method optimisation, troubleshooting complex analytical issues, and ensuring data integrity across the full study lifecycle. You will be accountable for the scientific oversight of studies, including data review, interpretation, and reporting to regulatory standards.

You will also play a key role in study planning, resource management, and delivery against timelines, quality, and cost expectations. Working closely with senior stakeholders, you will drive continuous improvement of LC-MS/MS workflows and laboratory processes, mentor scientific staff, and act as a technical escalation point. As a senior representative of the function, you will contribute to business development activities and support the growth and capability of the Laboratory Services team.

Key Accountabilities:

Provide technical advice to Business Development and participate in laboratory-related discussions with auditors, Sponsors and Simbec-Orion employees.
Act as a Laboratory Services Ambassador for Simbec-Orion, presenting at conferences, trade shows, and academic institutes whilst demonstrating the department's expertise.
Coordinate analytical studies from client onboarding to final reporting with accountability for the study’s regulatory compliance and scientific integrity.
Develop methods of analysis in order to deliver fully validated assays.
Support in mentoring and developing colleagues within the Laboratory Services department.
Ensure that work performed adheres to good practice regulations and guidelines associated with a laboratory environment. (e.g. GCP, EMA and FDA).
Document procedures undertaken in a clear, accurate and contemporaneous manner and apply Quality Control (QC) procedures to ensure their accuracy in accordance with the principles of ALCOA+.
Communicate the status of work performed with Laboratory Management, Laboratory Project Manager, and other team members.
Produce or review/approve relevant documentation such as protocols, procedures, validation/study reports, SOPs, CAPAs, and file notes.
Ensure all relevant study documents are delivered to the client and archived within expected timeframes.
Ensure the required resources are available to properly perform research tasks and ensure efficient use of consumables and instrumentation.
Maintain personal training records to demonstrate adequate competency for the position held associated responsibilities.

Skills Required:

ESSENTIAL

Degree in a scientific discipline or equivalent; advanced qualification desirable
Extensive experience using LC-MS/MS in a regulated laboratory environment (GCP, GLP, GMP)
Proven track record of leading LC-MS/MS-based studies, including method development, validation, and routine sample analysis
Deep technical expertise in mass spectrometry, including instrument setup, optimisation, maintenance, and troubleshooting
Strong understanding of bioanalytical method validation requirements and regulatory expectations
Demonstrable ability to ensure data integrity and compliance with GxP standards
Experience in reviewing and approving analytical data, reports, and study documentation
Proven ability to lead projects, manage priorities, and deliver to tight deadlines
Strong experience working to and interpreting protocols, SOPs, and regulatory guidelines
Excellent communication skills with the ability to engage internal teams, clients, and external stakeholders

DESIRABLE

MSc or PhD in a relevant discipline
Experience within a CRO or clinical trial environment
Knowledge of MHRA Phase I Accreditation scheme requirements
Experience in process improvement, operational efficiency, or workflow optimisation
Project management or Lean/Six Sigma certification
Experience supporting audits, inspections, and regulatory submissions
Line management or mentoring experience within a scientific team

About Us:

Simbec-Orion is growing fast. To keep up with demand, we’re looking for the best people, from all areas of clinical development, to join our team.

We’re dedicated to bringing the latest advances in science to market. Exposure to truly innovative new drugs in patient populations with serious unmet medical needs is what drives our company – and your reason to be a part of it.

With experts from all disciplines under the same roof, you’ll work alongside some of the industry’s best. So if you’d like to further your career within challenging therapeutic areas in rare disease, oncology, or at our clinical pharmacology site, or laboratory services. We’re waiting to hear from you.

Apply Now

Refine Your Search

document specialist jobs in cardiff, crf

Principal Scientist

Commercial Contract Specialist

Consultant Cardiologist with an interest in Interventional Cardiology

Bid Co-ordinator

Securities Operations Services Specialist

Solution Architect

High Intensity Psychological Therapist

Cyber Security Vulnerability Manager

CAD Technician

Clinical Psychologist

Consultant Social Worker (IFSS)

Principal Marine Surveyor - Plan Approval

Costs Lawyer/Draftsman - Personal Injury

Locum Consultant in Intensive Care Medicine

Site Service Engineer

Advanced Practitioner Radiographer - Head and Neck

Heart Failure Service Clinical Nurse Specialist Lead

National Rental Driver

Fire Safety Team Leader

Senior Automation Engineer

I want to receive the latest job alerts for document specialist in cardiff, crf

Related Searches

Explore jobs in more locations

Jobseeker tools

Employer Tools

Browse

Stay Connected