Clinical laboratory scientist Work, Jobs in Wales (with Salaries)

Principal Scientist - Immunoassay & Clinical Biomarkers
Simbec-Orion —Merthyr Tydfil
- Full-time
- Management
- Doctoral degree
- Master's degree
Animal Technician (AT) - Schistosomiasis Drug Discovery
Aberystwyth University —Aberystwyth
- Weekend availability
- Hybrid work
- Doctoral degree
- Research
- University
- Annual leave
- Employee discount
5d
Principal Scientist - Small Molecule LC-MS/MS
Simbec-Orion —Merthyr Tydfil
- Full-time
- Doctoral degree
- Master's degree
- Team management
1d
Consultant Haematologist
Cwm Taf Morgannwg University Health Board —Merthyr Tydfil
- £114,099 - £166,585 a year
- Full-time
- University

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Principal Scientist - Immunoassay & Clinical Biomarkers

Simbec-Orion -
Merthyr Tydfil

Apply Now

Job details

Permanent | Full-time

Qualifications

GLP
Management
Doctoral degree
Mentoring junior staff
Master's degree
Mentoring
Clinical trials
Good Clinical Practice (GCP)
Certified Project Manager
Good Clinical Practice (ICH-GCP) guidelines

Full job description

Our Mission:

Simbec-Orion is a responsive and agile full-service CRO, with wide therapeutic experience and specialist expertise in clinical pharmacology, oncology and rare diseases. Perfectly structured, we provide full-service clinical development solutions for small and mid-size drug developers – headed up by a centralised leadership team.

With a focus on tailormade and scalable solutions, we’ll adapt our delivery style, communications and operations to suit the demands of the project, helping clients achieve their clinical and commercial objectives. Because our goal is the same as theirs; to improve patients’ lives.

The Role:

We're looking for a Principal Scientist to lead immunoassay and clinical biomarker work within our Laboratory Services team, using platforms including ELISA and Ella (SimplePlex) to support studies across oncology, rare disease and clinical pharmacology. You'll take ownership of assay development and validation, troubleshoot complex biomarker and cytokine panel work, and act as the technical authority for the studies you run.

This role sits close to the clinic, your work directly informs patient stratification and treatment response data. You'll mentor the wider team on immunoassay technique and represent Laboratory Services in front of clients, auditors and inspectors.

Key Accountabilities:

Lead immunoassay development and validation across ELISA and Ella (SimplePlex) platforms
Troubleshoot assay performance issues including matrix interference, parallelism and dilutional linearity
Take scientific accountability for assigned studies: data integrity, regulatory compliance, and final reporting
Review and approve protocols, validation reports, SOPs and study documentation
Mentor scientists developing their immunoassay technique
Represent Laboratory Services with clients, auditors and Sponsors, and support Business Development with technical input

Skills Required:

ESSENTIAL

Extensive hands-on experience with plate-based immunoassays (ELISA) in a regulated laboratory environment (GCP, GLP and/or GMP)
Experience with the Ella (SimplePlex) platform or equivalent automated immunoassay systems
Proven track record leading assay development and validation for biomarker or cytokine panel work
Strong understanding of immunoassay-specific validation parameters (parallelism, dilutional linearity, matrix interference)
Demonstrable ability to review and approve technical documentation to GxP standard
Experience managing study timelines and priorities under deadline pressure

DESIRABLE

MSc or PhD in a relevant scientific discipline
CRO or clinical trial experience
Experience with multiplex cytokine panels
Six Sigma / Lean or project management certification
Experience supporting audits and regulatory inspections
Mentoring or informal line management experience

About Us:

Simbec-Orion is growing fast. To keep up with demand, we’re looking for the best people, from all areas of clinical development, to join our team.

We’re dedicated to bringing the latest advances in science to market. Exposure to truly innovative new drugs in patient populations with serious unmet medical needs is what drives our company – and your reason to be a part of it.

With experts from all disciplines under the same roof, you’ll work alongside some of the industry’s best. So if you’d like to further your career within challenging therapeutic areas in rare disease, oncology, or at our clinical pharmacology site, or laboratory services. We’re waiting to hear from you.

Apply Now

Refine Your Search

clinical laboratory scientist jobs in wales

Principal Scientist - Immunoassay & Clinical Biomarkers

Animal Technician (AT) - Schistosomiasis Drug Discovery

Principal Scientist - Small Molecule LC-MS/MS

Consultant Haematologist

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