In structural biology Work, Jobs in London (with Salaries)

Research Associate in Structural Biology
Imperial College London —South Kensington
- £49,017 - £57,472 a year
- Full-time
- Doctoral degree
- Leadership
- Communication skills
Research Scientist, Radiobiology
Bicycle Therapeutics —London
- Full-time
- Hybrid work
- Organisational skills
- Communication skills
- Annual leave
- Employee assistance programme
Quick apply
3d
Research Technician (Media Preparation Facility) - 0.5fte job share
University College London —London
- £36,433 - £41,833 a year
- Part-time
- Laboratory experience
- Bachelor's degree
- Organisational skills
- Annual leave
- Employee assistance programme
6d
Full-time PhD studentship (Chain & Yong Group)
University College London —London
- £24,643 a year
- Full-time
- Computer Science
- Master's degree
- Maths
5d
Regional Research Economist, Economic Research
Anthropic —London
- £180,000 - £190,000 a year
- Hybrid work
- Doctoral degree
- Data analysis skills
- SQL
- Flexible schedule
14d
Fleming Initiative Research Associate in High-Throughput Medicinal Chemistry
Imperial College London —White City
- £49,017 - £57,472 a year
- Full-time
- Doctoral degree
- Machine learning
Assistant Technician - Media Preparation Facility
University College London —London
- £31,904 - £35,575 a year
- Full-time
- Laboratory experience
- Organisational skills
- Communication skills
- Annual leave
- Employee assistance programme
12d
Scientific Director, Biologics, Discovery and Development
LifeArc —London
- Full-time
- Doctoral degree
- Analysis skills
- Organisational skills
- Annual leave
Senior Scientist, In Vivo Pharmacology (Radiopharmaceuticals)
Bicycle Therapeutics —London
- Full-time
- Remote
- Organisational skills
- Communication skills
- Annual leave
- Employee assistance programme
Quick apply
3d
Research Technical Manager
University College London —London
- £54,931 - £64,644 a year
- Full-time
- Laboratory experience
- Master's degree
- Annual leave
- Employee assistance programme
6d
Postdoctoral Researcher
Birkbeck University of London —London
- £44,247 - £50,379 a year
- Full-time
- Doctoral degree
- University
- Annual leave
7d
Associate Director / Director, Medicinal Chemistry (ADCs)
Pharmaron —Hoddesdon
- Doctoral degree
- Leadership
6d
Senior Scientist CADD Antibody Design Developer
UCB —Slough
- Doctoral degree
- English
- Machine learning
Senior Scientist - CADD, Digital Antibody Design
UCB —Slough
- Doctoral degree
- English
- Machine learning

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Research Associate in Structural Biology

Imperial College London -
South Kensington

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Job details

Full-time
£49,017 - £57,472 a year

Benefits

Company pension

Qualifications

Doctoral degree
Biochemistry
Microscopy
Leadership
Communication skills

Full job description

Job number

NAT02149

Faculties

Faculty of Natural Sciences

Departments

Department of Life Sciences

Salary or Salary range

£49,017 - £57,472 per annum

Location/campus

South Kensington Campus - On site only

Contract type work pattern

Full time - Fixed term

Posting End Date

28 Jun 2026

About the role

The Costa Laboratory (https://profiles.imperial.ac.uk/t.costa), in the Department of Life Sciences (https://www.imperial.ac.uk/life-sciences), Imperial College London, invites applications for a highly motivated and enthusiastic Research Associate with strong expertise in protein biochemistry and structural biology.

This position is funded by Wellcome Trust Discovery Award and focuses on elucidating the molecular mechanisms of horizontal gene transfer (HGT), including bacterial conjugation and bacteriophage-mediated transduction. You will join an interdisciplinary and collaborative team of structural biologists, membrane biochemists, and microbiologists addressing fundamental and long-standing questions in HGT biology.

The project centres on cryo–electron microscopy (cryo-EM) studies of the macromolecular nanomachines that drive conjugation, as well as bacteriophages and phage satellites responsible for transduction. The research builds on the laboratory’s strong track record in structural characterisation of Type IV secretion systems (Amin et al. Nat Commun 2021; Patkowski et al. Nat Commun 2023; Wong et al. Nat Commun 2025) and in phage and satellite biology (He et al. Cell 2025; Penades et al. Cell 2025).

You will benefit from extensive collaboration with group members specialising in cryo-EM, biochemistry, and biophysical approaches, fostering a dynamic and highly productive research environment. The laboratory is exceptionally well equipped for structural EM, with in-house access to: Glacios 200 kV XFEG cryo-EM with Falcon 4 and Selectris energy filter; Vitrobot IV and Leica GP2; dedicated state-of-the-art GPU and data storage cluster; direct access to a Titan Krios to the LonCEN consortium and the UK national cryo-EM facility at eBIC.

What you would be doing

By joining the Costa laboratory, you will become part of a supportive, yet ambitious research environment dedicated to enabling impactful discoveries and the production of world-class publications. The laboratory is well funded and underpinned by state-of-the-art facilities, providing an exceptional platform for innovative and high-quality research. The postholder will contribute to high-profile projects at the forefront of molecular microbiology and structural biology, while receiving direct mentorship from Dr Costa in grant writing, scientific networking, and publication strategy. There will be opportunities to present research at national and international conferences, fostering visibility and the development of a strong academic network. Located within a world-leading institution, the position offers an outstanding environment in which to develop scientific leadership skills and build a competitive profile. The laboratory’s scientific framework and structured support are specifically designed to facilitate career progression and a successful transition to research independence.

What we are looking for

You will have a PhD (or equivalent) in structural biology, with solid experience in cryo electron microscopy. You must have strong experience in the design and execution of end-to-end workflows for protein structure determination, encompassing molecular biology and biochemical approaches, through cryo-electron microscopy (cryo-EM) workflows, including grid preparation, and single-particle analysis (SPA) data acquisition, processing, and atomic model building.

Strong research track record, evidenced by at least one first-author publication in an international peer-reviewed journal or as a preprint on bioRxiv.

You must have excellent verbal and written communication skills, and be able to write clearly and succinctly for publication. You must also be able to relate well with others, form positive relationships with a wide range of people and to work as part of a team, as well as independently. The ability to develop and apply new concepts and have a creative approach to problem-solving, to set and attain research objectives in a multidisciplinary team are also essential.

What we can offer you

The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.
Grow your career: Gain access to Imperial’s sector-leading dedicated career support for researchers as well as opportunities for promotion and progression
Sector-leading salary and remuneration package (including 41 days off a year and generous pension schemes).

Further information

This is a full-time, fixed-term appointment available for up to 36 months.

Please note this is a re-advertisement; previous applicants need not apply.

Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant.

If you require any further details on the role please contact: Professor Tiago Dias da Costa – [email protected].

Available documents

Attached documents are available under links. Clicking a document link will initialize its download.

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities mentioned above.

We reserve the right to close the advert prior to the closing date stated should we receive a high volume of applications. It is therefore advisable that you submit your application as early as possible to avoid disappointment.

If you encounter any technical issues while applying online, please don't hesitate to email us at [email protected]. We're here to help.

About Imperial

Welcome to Imperial, a global top ten university where scientific imagination leads to world-changing impact.

Join us and be part of something bigger. From global health to climate change, AI to business leadership, here at Imperial we navigate some of the world’s toughest challenges. Whatever your role, your contribution will have a lasting impact.

As a member of our vibrant community of 22,000 students and 8,000 staff, you’ll collaborate with passionate minds across nine London campuses and a global network.

This is your chance to help shape the future. We hope you’ll join us at Imperial College London.

Our Culture

We work towards equality of opportunity, to eliminating discrimination, and to creating an inclusive working environment for all. We encourage applications from all backgrounds, communities and industries, and are committed to employing a team that has diverse skills, experiences and abilities. You can read more about our commitment on our webpages.

Our values are at the root of everything we do and everyone in our community is expected to demonstrate respect, collaboration, excellence, integrity, and innovation.

Apply Now

Refine Your Search

in structural biology jobs in london

Research Associate in Structural Biology

Research Scientist, Radiobiology

Research Technician (Media Preparation Facility) - 0.5fte job share

Full-time PhD studentship (Chain & Yong Group)

Regional Research Economist, Economic Research

Fleming Initiative Research Associate in High-Throughput Medicinal Chemistry

Assistant Technician - Media Preparation Facility

Scientific Director, Biologics, Discovery and Development

Senior Scientist, In Vivo Pharmacology (Radiopharmaceuticals)

Research Technical Manager

Postdoctoral Researcher

Associate Director / Director, Medicinal Chemistry (ADCs)

Senior Scientist CADD Antibody Design Developer

Senior Scientist - CADD, Digital Antibody Design

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