Job Title: Senior Statistician I
Location: Cambridge, UK
Salary: Competitive + Excellent Employee Benefits!
Introduction to role:Are you ready to turn complex data into clear decisions that move new medicines forward for patients? Do you want your statistical expertise to be visible across programs and influence design choices from day one?
At AstraZeneca, our CVRM Biometrics teams are at the forefront of delivering the data-driven insights that power breakthrough science. Working across clinical development, regulatory strategy, and cross-functional project teams, this area brings together deep expertise in statistics, quantitative sciences, and evidence generation to support the development of innovative medicines for patients living with cardiovascular, renal and metabolic diseases.
As a Senior Statistician I, you will work independently on standard studies and partner closely with senior statisticians on more complex programs. You will join a cross-functional community that values clear thinking, constructive challenge and pace—helping shape study designs, strengthen evidence, and increase confidence in pivotal decisions. Your work will be recognized across multiple therapy areas, with opportunities to broaden impact as you grow.
You will contribute where rigor matters most: designing robust studies, building analysis plans that stand up to scrutiny, and translating results into insights that guide development. Here, every critique sharpens our approach and every analysis helps us learn faster—because patients cannot wait.
Accountabilities:
- Study Design and Interpretation: Provide independent statistical input to standard study designs and data interpretation to ensure scientifically sound decisions and efficient execution.
- Complex Program Support: Under the guidance of a more experienced statistician, design and analyze complex studies and support broader programs, including high-stakes regulatory submissions, commercialization activities and key internal governance interactions.
- Evidence Integration and Decision Criteria: Under guidance, analyze internal and external information to inform design decisions and establish decision criteria that improve confidence and clarity.
- Modelling and Simulation: Apply modelling and simulation to optimize study design, test assumptions and assess the robustness of results before and after execution.
- Statistical Analysis Planning: Develop Statistical Analysis Plans that are fit for purpose and inspection-ready for study and/or project delivery.
- Analysis and Reporting: Produce analyses, graphics and tables for standard studies, enabling high-quality clinical study reports and publications delivered on time.
- Results Translation: Interpret, summarize and communicate results of standard studies in plain language for multidisciplinary stakeholders to drive action.
- Methodology and Process Improvement: Contribute to methodological advances and practical solutions that improve quality, efficiency and effectiveness across projects.
- Ways of Working: Apply statistical methodology to streamline processes and improve delivery predictability and reproducibility.
- Best Practice and Quality Ownership: Shape and adopt best practices; be accountable for the quality of your statistical work, bringing discipline-specific insight and constructive challenge while actively developing your capabilities.
Essential Skills/Experience:
- MSc/PhD in Statistics, Mathematics (containing a substantial statistical component), or recognised equivalent to stats MSc.
- Competent statistical programmer (SAS and R).
- Knowledge of key technical and regulatory requirements.
- Experience of design, analysis and reporting of preclinical or clinical studies in more than one setting.
- Communication skills.
- Collaboration and team working skills.
Desirable Skills/Experience:
- Ability to apply statistical expertise to problems, problem solving and quality focus.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
Why AstraZeneca?Join a company where rigorous science meets real-world impact. You will operate with high visibility and growing responsibility, shaping deliverables that influence key decisions across global therapy areas. Expect a collaborative environment that brings diverse minds together, uses advanced tools and technology to solve tough problems, and recognizes both progress and learning. We balance bold ambition with support—valuing curiosity, resilience and kindness—so you can stretch your skills, contribute to breakthroughs and see the patient impact of your work.
Step into a high-visibility role where your statistics accelerate life-changing medicines—send your CV today to start shaping smarter study designs and stronger decisions.
Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
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Date Posted
23-Jun-2026
Closing Date
07-Jul-2026
Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
