Senior science Work, Jobs in Sheffield, Eng (with Salaries)

Senior Bioinformatician
SynGenSys Limited —Sheffield
- From £52,000 a year
- Full-time
- Hybrid work
- Doctoral degree
- Data analysis skills
- Master's degree
- Life insurance
- Sick pay
Quick apply
14d
Student Experience Manager
University of Sheffield —Sheffield
- £38,784 - £47,389 a year
- Part-time
- Hybrid work
- Customer service
- Microsoft Office
- University
- Annual leave
- Employee discount
5d
Senior Team Leader - Analytical
Concept Life Sciences —Chapel en le Frith
- Full-time
- Doctoral degree
- Analysis skills
- Travel
- Free parking
Senior Science Technician
Redhill Academy Trust —Chesterfield
- £9,375.49 - £10,166.02 a year
- Laboratory experience
- Organisational skills
- School
- Annual leave
- Employee assistance programme
6d
Health and Safety Manager
The Sheffield College —Sheffield
- £47,578 - £52,457 a year
- 8 hour shift
- Management
- Communication skills
- Free parking
- Annual leave
4d
Senior Science Technician
Maltby Learning Trust —Rotherham
- £25,958 - £31,537 a year
- Laboratory experience
- Organisational skills
- Leadership
13d
SHE Manager
Victrex —Rotherham
- £63,500 - £71,500 a year
- Management
- Engineering
- Analysis skills
Policy Impact Officer
University of Sheffield —Sheffield
- £38,784 - £43,482 a year
- Full-time
- Hybrid work
- Project management
- Bachelor's degree
- Mentoring
- Annual leave
- Employee discount
Senior Project Engineer
University of Sheffield —Rotherham
- £38,784 - £51,753 a year
- Full-time
- Hybrid work
- CAD
- Engineering
- Microsoft Office
- Annual leave
- Employee discount
Support Technician
University of Sheffield —Sheffield
- £25,249 - £26,707 a year
- Full-time
- Hybrid work
- University
- Communication skills
- School
- Annual leave
- Employee discount
11d
Junior Integration Engineer
Ericsson —Sheffield
- Azure
- Laboratory experience
- Java
3h
Junior Ecologist (full time)
Whitcher Wildlife Limited —Barnsley
- £26,000 - £29,000 a year
- Full-time
- Data analysis skills
- English
- In-person
Quick apply
Senior Scientist I
Charles River Laboratories —High Peak
- Full-time
- Doctoral degree
- Sales
- Laboratory experience
8d
Senior Implementation Engineer
Arm —Sheffield
- £73,500 - £99,500 a year
- Hybrid work
- Linux
- AI
- Leadership
- Relocation assistance
Junior RAN Test Engineer
Ericsson —Sheffield
- Azure
- Laboratory experience
- Java
3h
Science Technician
Maltby Learning Trust —Rotherham
- £22,238 - £25,989 a year
- Organisational skills
- Communication skills
Research Associate in Algebraic Number Theory
University of Sheffield —Sheffield
- £38,784 - £47,389 a year
- Full-time
- Hybrid work
- Doctoral degree
- Maths
- University
- Annual leave
- Employee discount
13d
Assistant Headteacher - Permanent
Kingsland Primary School —Wakefield
- £61,534 - £67,898 a year
- Full-time
- Bachelor's degree
- In-person
- Leadership
Quick apply
7d
Scientist - Analytical Chemistry and Biological Monitoring (Band 5/EO)
Health and Safety Executive —Buxton
- £31,657 - £34,570 a year
- Part-time
- Data analysis skills
- Laboratory experience
- Analysis skills
11d
Teacher of Science
Outwood Grange Academies Trust —Chesterfield
- Part-time
- School
- Teaching
- Employee assistance programme

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Senior Bioinformatician

SynGenSys Limited
Sheffield

Quick apply

Job details

Permanent | Full-time
From £52,000 a year
14 days ago

Benefits

Company pension
Private medical insurance
Life insurance
Sick pay

Qualifications

Doctoral degree
R
Data analysis skills
Git
Master's degree
Bash (Unix shell)
SQL
AWS
Bachelor's degree
Machine learning
GitHub
Cloud computing
Python
HTML

Full job description

SynGenSys is a cutting-edge biotechnology company focused on developing innovative solutions for the design and manufacture of next-generation biomedicines. By leveraging synthetic genetic systems, we aim to improve biomanufacturing processes and enhance the safety and efficacy of cell and gene therapies and mRNA vaccines.

We are seeking a proactive, analytical, and highly motivated Senior Bioinformatician to join our dynamic team. The role will involve managing, analysing and interpreting complex biological datasets from both public repositories and in-house experimental studies. Close collaboration with other computational and laboratory scientists will be essential to ensure rapid and accurate data processing across projects. They will also contribute to the ongoing development of SynGenSys’ computational platform and support customer engagement and the commercialisation of SynGenSys technology.

The ideal candidate will have a BSc or equivalent with experience in bioinformatics, computational biology, or mathematical and statistical sciences with applications in bioinformatics and/or biostatistics, and a proven track record of project delivery, ideally in an commercial setting. Strong expertise in multi-omics data analysis, including data quality control, processing, interpretation and integration of different data types is essential. Proficiency in bioinformatics-relevant programming languages is required, alongside a solid understanding of biological processes and experimental design.

Key Responsibilities

Maintain and improve in-house bioinformatics workflows to enhance scalability, performance, and usability.
Support the onboarding, optimisation and further development of computational tools used by multidisciplinary teams across SynGenSys.
Manage multiple projects concurrently, ensuring timelines are met and results are delivered in a timely manner.
Maintain structured project documentation, standardised reporting practices, and rigorous record-keeping to ensure reproducibility and consistency across analyses.
Generate detailed reports, visualisations, and presentations for both internal teams and external partners, providing clear explanations of analytical methods and results.
Coordinate with laboratory scientists to ensure smooth data transfer and effective communication of analysis results to non-experts.
Provide technical support to fellow computational scientists to strengthen collaboration and complementary expertise across the team.
Support engagement with stakeholders, customers and partners to contribute to the commercialisation of SynGenSys’ platform and products.

Essential Qualifications and Skills

BSc/MSc degree or equivalent in bioinformatics, computational biology or a closely related discipline, with extensive experience in a commercial setting.
Strong understanding of at least two from the following: genomics, transcriptomics, proteomics and mammalian cell biology.
Experience in the analysis and interpretation of omics and other biological datasets using statistical and visualisation approaches.
Proficiency in at least two of R, Python and/or Bash scripting, with demonstrable ability to automate data analysis pipelines and write reproducible code.
Hands-on experience with workflow management systems (e.g., CGAT, Nextflow) for building and managing pipelines.
Familiarity with environment management tools (e.g., Conda) to handle dependencies and ensure reproducible computational environments.
Experience analysing high-throughput sequencing data (e.g., bulk and single-cell RNA-Seq, ChIP-Seq, ATAC-Seq)
Familiarity with bioinformatics analysis tools and packages (e.g., STAR, DESeq2).
Ability to work under pressure, manage multiple projects with changing priorities and meet deadlines.
Strong attention to detail and problem-solving skills.

Desirable Skills

PhD in bioinformatics, computational biology, or mathematical and statistical sciences with applications in bioinformatics and/or biostatistics.
Past experience developing software in a commercial setting for use in a regulated environment.
Knowledge of regulatory genomics and transcription factor resources (e.g., JASPAR, TFLink) and/or pathway analysis tools (e.g., KEGG, Reactome).
Experience with large-scale public biological datasets (e.g., NCBI, ENCODE, TCGA).
Experience in design of experiments (DoE) and/or massively parallel reporter assays (MPRA), including analysis of MPRA datasets.
Strong understanding of statistical methods applied to biological data analysis.
Application of machine learning (ML) methods to biological datasets.
Experience with high-performance computing (HPC), job schedulers (e.g. SLURM) and parallel computing.
Ability to generate professional reports in reproducible formats (e.g., R Markdown, HTML, PDF).
Version control using Git/GitHub.
Familiarity with cloud computing platforms (e.g., AWS, Google Cloud).
Familiarity with additional programming languages (e.g., SQL).

Working Environment

At SynGenSys, we foster a collaborative, inclusive, and fast-paced environment where innovation thrives. You will have the opportunity to work with cutting-edge technologies and contribute to impactful research that has real-world applications in biopharmaceutical manufacturing and medicine. As part of our dynamic team, you will be expected to grow professionally and personally, while making meaningful contributions to the company's goals.

Located in Sheffield, you’ll be close to the Peak District National Park, giving you a great balance of city life and natural surroundings. The Peak District offers a wide range of outdoor activities, including hiking, climbing, cycling, and caving, making it an ideal place for adventure and exploration outside of work.

Hybrid working arrangements are available, with attendance required at times, particularly for meetings and collaborative work.

Benefits

Competitive salary
Salary Sacrifice Pension Scheme
Cash health plan
Death in service
Enhanced paid sick leave
Flexible working

Application Process

To apply submit your CV and any additional information (cover letter, portfolio, or relevant work samples) to [email protected]. Applications will be reviewed on a rolling basis. Suitable candidates will be invited to Sheffield to meet members of the team and discuss the role at interviews

SynGenSys is an equal opportunity employer. We value diversity and are committed to creating an inclusive environment for all employees. We encourage individuals from all backgrounds to apply

Pay: From £52,000.00 per year

Benefits:

Life insurance
Private medical insurance
Sick pay

Work Location: Hybrid remote in Sheffield

Quick apply

Refine Your Search

senior science jobs in sheffield, eng

Senior Bioinformatician

Student Experience Manager

Senior Team Leader - Analytical

Senior Science Technician

Health and Safety Manager

Senior Science Technician

SHE Manager

Policy Impact Officer

Senior Project Engineer

Support Technician

Junior Integration Engineer

Junior Ecologist (full time)

Senior Scientist I

Senior Implementation Engineer

Junior RAN Test Engineer

Science Technician

Research Associate in Algebraic Number Theory

Assistant Headteacher - Permanent

Scientist - Analytical Chemistry and Biological Monitoring (Band 5/EO)

Teacher of Science

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